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Table 2 Clinical characteristics in the MCCD cohort

From: Polygenic risk for coronary heart disease acts through atherosclerosis in type 2 diabetes

 Patients (n = 352)Patients with information (%)
Multivessel stenosis (%)236 (67.1)352 (100)
Median number of significant lesions (IQR)2 (1–4)352 (100)
Severity of atherosclerosis 352 (100)
 0–1 (%)116 (33.0) 
 2 (%)68 (19.3) 
 3 (%)61 (17.3) 
  ≥ 4 (%)107 (30.4) 
Mean PRSa (SD)17.18 (0.10)352 (100)
Men (%)269 (76.4)352 (100)
Median age (IQR)71 (66–78)352 (100)
European (%)310 (88.1)352 (100)
Hypertension (%)328 (93.2)352 (100)
 Systolic hypertension (%)149 (42.7)349 (99.1)
 Diastolic hypertension (%)16 (4.6)349 (99.1)
 Antihypertensive drug usage (%)311 (88.4)352 (100)
Hyperlipidemia (%)333 (94.9)351 (99.7)
 High LDL (%)146 (42.8)341 (96.9)
 Hypertriglyceridemia (%)2 (0.5)347 (98.6)
 Lipid-lowering drug usage (%)296 (84.1)352 (100)
Poor glycemic control (%)48 (14.0)343 (97.4)
Median BMI (IQR)29.82 (26.15–33.90)346 (98.3)
Ex- or current smokersb (%)197 (56.0)352 (100)
Median type 2 diabetes durationb (IQR)15 (8–22)189 (53.7)
Median age of type 2 diabetes diagnosisb (IQR)58 (47–64)189 (53.7)
Family history of heart diseaseb (%)209 (73.9)283 (83.4)
  1. aOriginal PRS is reported in this table. Downstream analyses adopted standardized PRS
  2. bBased on self-reported medical histories