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Table 1 Clinical characteristics in the population of British ancestry in the UK Biobank with type 2 diabetes

From: Polygenic risk for coronary heart disease acts through atherosclerosis in type 2 diabetes

 Participants (n = 21,102)Participants with information (%)
CHD (%)1898 (9.0)21,102 (100)
Mean CHD PRSa (SD)16.49 (0.08)21,102 (100)
Men (%)13,010 (61.7)21,102 (100)
Median age (IQR)62 (56–66)21,102 (100)
Hypertension (%)14,899 (70.6)21,102 (100)
 Systolic hypertension (%)10,837 (54.6)19,866 (94.1)
 Diastolic hypertension (%)3551 (17.9)19,866 (94.1)
 Antihypertensive drug usage (%)8697 (41.2)21,102 (100)
Hyperlipidemia (%)19,964 (94.6)21,102 (100)
 High LDL (%)18,280 (91.2)20,035 (94.9)
 Hypertriglyceridemia (%)418 (2.0)20,055 (95.0)
 Lipid-lowering drug usage (%)10,077 (47.8)21,102 (100)
Poor glycemic control (%)3406 (16.9)20,171 (95.6)
Median BMI (IQR)30.80 (27.50–34.80)20,347 (96.4)
Smoking history (%)14,039 (66.9)20,971 (99.4)
Family history of heart disease (%)10,560 (50.0)21,102 (100)
  1. a Non-standardized PRS is reported in this table to allow comparison with other cohorts. All subsequent analyses adopted standardized PRS