Triglyceride–glucose index is associated with the risk of myocardial infarction: an 11-year prospective study in the Kailuan cohort

Table 4 Subgroup analysis for the risk of myocardial infarction by baseline TyG index (impact of TyG Q4)

Variables	Group	Model 1		Model 2		Model 3
Variables	Group	HR (95% CI)	P_interaction	HR (95% CI)	P_interaction	HR (95% CI)	P_interaction
Age
< 60 years	Q4	2.69 (2.15–3.35)	0.1428	2.39 (1.90–3.00)	0.2935	2.12 (1.69–2.68)	0.3000
≥ 60 years	Q4	2.43 (1.95–3.02)		2.25 (1.79–2.83)		1.94 (1.53–2.45)
Sex
Women	Q4	5.29 (2.70–10.37)	0.0128	5.13 (2.59–10.18)	0.0164	3.77 (1.86–7.64)	0.0411
Men	Q4	2.47 (2.11–2.90)		2.20 (1.86–2.60)		1.93 (1.63–2.29)
Diabetes
No	Q4	2.57 (2.19–3.02)	0.1352	2.28 (1.93–2.69)	0.1430	2.09 (1.77–2.47)	0.1138
Yes	Q4	1.56 (0.68–3.57)		1.64 (0.71–3.80)		1.54 (0.66–3.57)
BMI
< 28 kg/m²	Q4	2.65 (2.23–3.14)	0.3394	2.43 (2.04–2.90)	0.2573	2.08 (1.74–2.49)	0.4420
≥ 28 kg/m²	Q4	2.30 (1.48–3.58)		2.30 (1.48–3.58)		2.07 (1.32–3.23)

BMI body mass index, CI confidence interval, HR hazard ratio, TyG triglyceride glucose
Model 1, adjusted for age and sex at baseline other than the variable for stratification
Model 2, adjusted for variables in model 1 plus level of education, income, smoking, alcohol abuse, physical activity, and BMI at baseline other than the variable for stratification
Model 3, adjusted for variables in model 2 plus SBP, DBP, a history of hypertension, diabetes mellitus, and dyslipidemia, antidiabetic drugs, lipid-lowering drugs, antihypertensive drugs, HDL-C, LDL-C, and hs-CRP at baseline other than the variable for stratification

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