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Fig. 3 | Cardiovascular Diabetology

Fig. 3

From: Dual SGLT-1 and SGLT-2 inhibition improves left atrial dysfunction in HFpEF

Fig. 3

a Representative examples of electrically (1 Hz; left) and caffeine-induced (20 mM; right) CaT. Tau of decay was determined during electric stimulation (left; blue curvature) and after caffeine (right; orange curvature). Blue arrows indicate electric stimulation triggers, orange arrows indicate caffeine application. Related data of b SR Ca2+ load, c tau of electrically stimulated CaT (d), tau of caffeine-induced CaT and e NCX forward-mode activity (calculated from c and d, see “Methods”). Statistical analysis: two-way ANOVA followed by post-hoc Bonferroni. p-values: 10.008, 20.01, 30.01. n = cells derived from 6 animals per group

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