Skip to main content

Table 3 Association between quartiles of the MEDLIFE index and risk of all-cause and cardiovascular death over 8.7 years of follow-up

From: Association between the Mediterranean lifestyle, metabolic syndrome and mortality: a whole-country cohort in Spain

  Categories of adherence to MEDLIFE p for trend Per +2-point increment
Q1 (4–11 p) Q2 (12–13 p) Q3 (14–15 p) Q4 (16–23 p)
All-cause mortality
 N 3042 3435 2917 1696   
 Deaths 118 106 76 30   
 Person-years 9,716,596 10,978,581 9,323,908 5,381,351   
 Model 1, HR (95% CI) 1 Ref. 0.92 (0.70, 1.21) 0.68 (0.48, 0.95) 0.54 (0.36, 0.83) 0.004 0.87 (0.79, 0.96)
 Model 2, HR (95% CI) 1 Ref. 0.91 (0.69, 1.22) 0.70 (0.49, 0.99) 0.55 (0.36, 0.85) 0.010 0.88 (0.80, 0.97)
 Model 3, HR (95% CI) 1 Ref. 0.88 (0.65, 1.18) 0.68 (0.48, 0.96) 0.55 (0.35, 0.85) 0.014 0.88 (0.79, 0.97)
 Model 4, HR (95% CI) 1 Ref. 0.92 (0.68, 1.25) 0.72 (0.51, 1.02) 0.58 (0.37, 0.90) 0.025 0.89 (0.81, 0.99)
CVD mortality
 Deaths 29 21 19 5   
 Person-years 9,716,596 10,978,581 9,323,908 5,381,351   
 Model 1, HR (95% CI) 1 Ref. 0.50 (0.27, 0.93) 0.72 (0.37, 1.37) 0.26 (0.08, 0.79) 0.02 0.78 (0.64, 0.97)
 Model 2, HR (95% CI) 1 Ref. 0.55 (0.29, 1.04) 0.82 (0.42, 1.58) 0.30 (0.10, 0.94) 0.06 0.82 (0.67, 1.01)
 Model 3, HR (95% CI) 1 Ref. 0.55 (0.28, 1.07) 0.83 (0.43, 1.62) 0.31 (0.10, 0.94) 0.08 0.83 (0.68, 1.02)
 Model 4, HR (95% CI) 1 Ref. 0.57 (0.29, 1.14) 0.87 (0.44, 1.70) 0.33 (0.11, 1.02) 0.11 0.84 (0.68, 1.04)
  1. The ENRICA cohort, June 2008 to December 2017
  2. Number of morbidities includes the following self-reported physician-diagnosed diseases (coronary heart disease, stroke and heart failure, osteoarthritis, rheumatoid arthritis, respiratory disease, hip fracture, urinary infection, sleep apnea, depression, Alzheimer’s disease, cirrhosis, Parkinson’s disease, stomach ulcers, intestinal polysp, cataracts, periodontal disease, cancer)
  3. Model 1: adjusted for sex, age, educational level (no formal or primary education, secondary education, university)
  4. Model 2: adjusted for Model 1 + smoking (never, former, current), total energy intake (Kcal/day), and BMI
  5. Model 3: Model 2 + prevalence of cancer, respiratory disease, depression, number of morbidities (excluding the previously mentioned conditions), number of drug treatments
  6. Model 4: Model 3 + other clinical risk factors, including abdominal obesity (waist circumference ≥ 102 cm in men, or ≥ 88 cm in women), fasting blood glucose (100–126 mg/dl and not treated with antidiabetic drugs), high blood pressure (systolic ≥ 130 mmHg or diastolic ≥ 85 mmHg) or receiving antihypertensive drugs, triglycerides ≥ 150 mg/dl and serum high-density lipoprotein (HDL) cholesterol < 40 mg/dl in men or < 50 mg/dl in women)
  7. HR hazard ratio, CI confidence interval