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Table 3 Hazard ratios and 95% confidence intervals for new-onset ischemic heart diseases according to TyG index quartiles

From: The triglyceride-glucose index predicts ischemic heart disease risk in Koreans: a prospective study using National Health Insurance Service data

 

TyG index quartiles

Q1

n = 4140

Q2

n = 4119

Q3

n = 4096

Q4

n = 4100

P for trend

New cases of ischemic heart disease, n

41

70

93

118

 

Mean follow-up, years

2.4 ± 1.1

2.4 ± 1.1

2.4 ± 1.1

2.4 ± 1.1

 

Pearson-years of follow-up

9878

9745

9651

9756

 

Incidence rate/1000 person -years

4.2

7.2

9.6

12.1

 

Model 1

1.00 (reference)

1.41 (0.96–2.08)

1.67 (1.15–2.42)

2.13 (1.48–3.06)

< 0.001

Model 2

1.00 (reference)

1.61 (1.05–2.48)

1.85 (1.21–2.81)

2.29 (1.50–3.51)

0.001

Model 3

1.00 (reference)

1.63 (1.06–2.49)

1.88 (1.23–2.87)

2.35 (1.53–3.61)

0.001

Model 4

1.00 (reference)

1.61 (1.05–2.48)

1.85 (1.21–2.83)

2.28 (1.48–3.51)

0.002

  1. TyG index triglyceride-glucose index
  2. * Multivariate cox proportional-hazards regression model analysis
  3. Model 1: adjusted for age and sex.
  4. Model 2: adjusted for age, sex, body mass index, smoking status, alcohol intake, and physical activity.
  5. Model 3: adjusted for age, sex, body mass index, smoking status, alcohol intake, physical activity, high sensitivity C-reactive protein, and mean arterial blood pressure, C-reactive protein level, and chronic kidney disease.
  6. Model 4: adjusted for age, sex, body mass index, smoking status, alcohol intake, physical activity, high sensitivity C-reactive protein, mean arterial blood pressure, C-reactive protein level, chronic kidney disease, and hypertension medication.