Cardiovascular Diabetology

Table 2 Spearman correlation analysis between baseline circulating PCSK9 and clinical characteristics

From: Association of circulating proprotein convertase subtilisin/kexin type 9 levels and the risk of incident type 2 diabetes in subjects with prediabetes: a population-based cohort study

Variables	Circulating PCSK9
	Total		Men		Women
	r	p value	r	p value	r	p value
Age	0.092*	0.001	0.077	0.109	0.197*	< 0.001
BMI	0.052	0.058	− 0.022	0.647	0.092*	0.006
Waist circumference	0.079*	0.004	− 0.018	0.707	0.144*	< 0.001
FPG	0.175*	< 0.001	0.116*	0.015	0.227*	< 0.001
PPG	− 0.011	0.679	− 0.105	0.107	0.037	0.275
HbA_1c	− 0.051	0.067	− 0.102	0.060	− 0.035	0.293
Insulin	0.045	0.105	− 0.069	0.151	0.093*	0.006
HOMA-IR	0.078*	0.005	− 0.041	0.400	0.133*	< 0.001
CRP	0.108*	0.002	0.062	0.273	0.126*	< 0.001
SBP	0.100*	< 0.001	0.085	0.077	0.129*	< 0.001
DBP	0.023	0.404	0.037	0.441	0.039	0.248
HDL-C	− 0.083	0.056	− 0.072	0.075	0.092	0.059
LDL-C	0.163*	< 0.001	0.128*	0.008	0.176*	< 0.001
Total cholesterol	0.248*	< 0.001	0.254*	< 0.001	0.239*	< 0.001
Triglycerides	0.190*	< 0.001	0.188*	< 0.001	0.203*	< 0.001
ALT	0.176*	< 0.001	0.127*	0.008	0.225*	< 0.001
AST	0.185*	< 0.001	0.214*	< 0.001	0.191*	< 0.001
GGT	0.168*	< 0.001	0.229*	< 0.001	0.207*	< 0.001
Cr	0.028	0.313	0.102*	0.033	0.073*	0.031
eGFR	− 0.060*	0.031	− 0.096*	0.045	− 0.045	0.188

BMI body mass index, FPG fasting plasma glucose, PPG postprandial plasma glucose, HbA_1c glycated hemoglobin, HOMA-IR homeostasis model assessment-insulin resistance, CRP C-reactive protein, SBP systolic blood pressure, DBP diastolic blood pressure, HDL-C high-density lipoprotein cholesterol, LDL-C low-density lipoprotein cholesterol, ALT alanine transaminase, AST aspartate transaminase, GGT γ-glutamyltransferase, Cr serum creatinine, eGFR estimated glomerular filtration rate
^* p < 0.05

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ISSN: 1475-2840

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