Composite event | Dulaglutide group | Placebo group | Events avoideda | Conditional time gap model | Proportional means model | ||
---|---|---|---|---|---|---|---|
N (/1000py) | N (/1000py) | N (N/1000py) | HR (95% CI) | p | HR (95% CI) | P | |
MACE or non-CV death | 932 (35.8) | 1040 (40.3) | 108 (4.5) | 0.90 (0.82–0.98) | 0.020 | 0.89 (0.80–0.98) | 0.022 |
MACE, UA or non-CV death | 1034 (39.7) | 1123 (43.5) | 89 (3.8) | 0.92 (0.85–1.00) | 0.052 | 0.91 (0.83–1.01) | 0.066 |
MACE, HF or non-CV death | 1195 (45.9) | 1372 (53.2) | 177 (7.3) | 0.91 (0.84–0.99) | 0.021 | 0.86 (0.78–0.96) | 0.006 |
MACE, Revasc or non-CV death | 1399 (53.8) | 1519 (58.9) | 120 (5.1) | 0.92 (0.86–0.99) | 0.030 | 0.91 (0.83–1.01) | 0.0632 |
MACE, UA, HF, Revasc or non-CV death | 1747 (67.1) | 1926 (74.7) | 179 (7.6) | 0.93 (0.87–0.99) | 0.023 | 0.90 (0.82–0.99) | 0.028 |