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Table 4 Univariable Cox-regression analysis for plaque-morphological parameters as predictors of mortality following coronary intervention

From: Prognostic irrelevance of plaque vulnerability following plaque sealing in high-risk patients with type 2 diabetes: an optical coherence tomography study

  HR (95% CI) p
Stenosis characteristics
 Percent area stenosis (per 10%) 0.89 (0.54–1.48) 0.665
 MLA (per mm2) 0.88 (0.45–1.73) 0.711
 MLD (per mm) 0.31 (0.04–2.41) 0.264
 Stenosis lumen eccentricity (per 10%) 1.61 (1.14–2.28) 0.007
Lesion morphology
 Lesion length (per 10 mm) 1.69 (1.07–2.68) 0.026
 Lipid plaque (presence) 0.78 (0.34–1.80) 0.559
 Calcific plaque (presence) 4.06 (1.20–13.72) 0.024
 Fibrous plaque (presence) 1.29 (0.30–5.52) 0.733
 Presence of TCFA (presence) 0.87 (0.32–2.34) 0.871
 Minimal FCT (per 10 µm) 0.98 (0.78–1.23) 0.877
 Mean FCT (per 10 µm) 1.10 (0.91–1.33) 0.336
 Lipid arc (per 10°) 0.95 (0.83–1.08) 0.435
 Lipid volume index (per 100°*mm) 0.95 (0.84–1.09) 0.481
 Presence of microchannels (presence) 0.99 (0.43–2.28) 0.974
Calcification morphology
 Presence of microcalcifications (presence) 0.71 (0.24–2.10) 0.539
 Number of microcalcifications (per calcification) 0.93 (0.51–1.69) 0.932
 Presence of spotty calcifications (presence) 0.52 (0.22–1.28) 0.155
 Number of spotty calcifications (per calcification) 0.90 (0.71–1.14) 0.386
 Presence of macrocalcifications (presence) 8.23 (1.11–61.11) 0.039
 Number of macrocalcifications (per calcification) 1.43 (1.14–1.79) 0.002
 Total number of calcifications (per calcification) 1.06 (0.92–1.22) 0.433
 Mean calcium arc (per 10°) 1.10 (1.03–1.19) 0.005
 Calcium length (per mm) 1.06 (1.02–1.11) 0.008
 Calcium volume index (per 1000°*mm) 1.62 (1.21–2.17) 0.001
Plaque inflammation
 Presence of macrophages (presence) 1.22 (0.54–2.77) 0.632
 Macrophage arc (per 10°) 0.95 (0.78–1.15) 0.605
 Macrophage length (per mm) 0.84 (0.38–1.24) 0.385
 Macrophage volume index (per 100°*mm) 0.59 (0.24–1.42) 0.233
  1. MLA minimal luminal area, MLD minimal luminal diameter, TCFA thin capped fibroatheroma, FCT fibrous cap thickness