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Table 2 Lesion characteristics and comparison between survivors and non-survivors

From: Prognostic irrelevance of plaque vulnerability following plaque sealing in high-risk patients with type 2 diabetes: an optical coherence tomography study

  Study population Survivors Non-survivors p
n = 81 n = 57 n = 24
Vessel
 LAD (n, %) 35 (43.2) 24 (42.2) 11 (45.8) 0.558
 CX (n, %) 13 (14.8) 11 (19.3) 1 (4.2) 0.558
 RCA (n, %) 30 (37.0) 19 (33.3) 11 (45.8) 0.558
 RIM (n, %) 4 (4.9) 3 (5.3) 1 (4.2) 0.558
Stenosis characteristics
 Percent area stenosis (%) 76.8 ± 8.0 82.0 ± 10.9 75.0 ± 15.6 0.536
 MLA (mm2) 1.4 ± 0.6 1.4 ± 0.7 1.3 ± 0.5 0.704
 MLD (mm) 1.1 ± 0.3 1.1 ± 0.3 1.0 ± 0.2 0.319
 Stenose lumen eccentricity (%) 25.4 ± 11.9 23.4 ± 10.2 30.2 ± 14.5 0.051
Lesion morphology
 Lesion length (mm) 15.7 ± 8.4 14.5 ± 8.1 18.7 ± 8.5 0.045
 Lipid plaque (n,%) 44 (54.3) 33 (57.9) 11 (47.8) 0.413
 Calcific plaque (n,%) 52 (64.2) 32 (56.1) 20 (87.0) 0.009
 Fibrous plaque (n,%) 71 (87.7) 50 (87.7) 21 (91.3) 0.646
 Presence of TCFA (n, %) 30 (37.0) 23 (40.4) 7 (33.3) 0.823
 Minimal FCT (µm) 66.3 ± 26.5 66.2 ± 26.1 66.8 ± 28.8 0.945
 Mean FCT (µm) 111.3 ± 29.3 108.4 ± 25.9 120.3 ± 38.1 0.244
 Lipid arc (°) 147.6 ± 45.8 151.3 ± 45.8 136.1 ± 46.0 0.343
 Lipid volume index (°*mm) 787.2 ± 477.0 824.9 ± 481.8 666.9 ± 462.1 0.344
 Presence of microchannels (n, %) 37 (45.7) 26 (46.4) 11 (47.8) 0.910
Calcification morphology
 Presence of microcalcifications (n, %) 15 (18.5) 11 (21.6) 4 (16.7) 0.621
 Number of microcalcifications 0.3 ± 0.7 0.3 ± 0.7 0.3 ± 0.7 0.902
 Presence of spotty calcifications (n, %) 60 (74.1) 43 (84.3) 17 (70.8) 0.173
 Number of spotty calcifications 2.1 ± 2.0 2.2 ± 2.1 1.8 ± 1.6 0.388
 Presence of macrocalcifications (n,%) 58 (71.6) 35 (68.6) 23 (95.8) 0.009
 Number of macrocalcifications 1.5 ± 1.3 1.2 ± 1.0 2.3 ± 1.5 < 0.001
 Total number of calcifications 4.0 ± 2.7 3.7 ± 2.8 4.4 ± 2.4 0.310
 Mean calcium arc (°) 79.4 ± 39.8 71.6 ± 33.7 95.9 ± 46.8 0.013
 Calcium length (mm) 12.3 ± 8.3 10.7 ± 8.0 15.9 ± 8.3 0.010
 Calcium volume index (°*mm) 1133.5 ± 1093.1 877.4 ± 908.5 1677.9 ± 1263.2 0.003
Plaque inflammation
 Presence of macrophages (n, %) 31 (38.3) 20 (37.7) 11 (45.8) 0.502
 Macrophage arc (°) 15.1 ± 21.7 15.7 ± 23.4 13.7 ± 17.7 0.704
 Macrophage length (mm) 0.8 ± 1.2 0.8 ± 1.3 0.6 ± 0.8 0.358
 Macrophage volume index (°*mm) 39.5 ± 15.7 41.0 ± 77.8 20.5 ± 32.0 0.109
  1. LAD left anterior descending, CX ramus circumflexus, RCA right coronary artery, RIM ramus intermedius, MLA minimal luminal area, MLD minimal luminal diameter, TCFA thin capped fibroatheroma, FCT fibrous cap thickness