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Fig. 1 | Cardiovascular Diabetology

Fig. 1

From: Renoprotection with SGLT2 inhibitors in type 2 diabetes over a spectrum of cardiovascular and renal risk

Fig. 1

The renal risk spectrum in T2D. a In addition to hyperglycemia, a range of other conditions can increase the risk of adverse renal events in T2D, such as AKI incidents, HU, and prolonged HK. b CKD amplifies the risk of adverse CV outcomes at any stage. In addition to developing along its own continuum, CKD acts as an amplifier of CV risk, as shown in the rear projection, which highlights that the presence of CKD of any stage increases a person’s CV risk, and that the more advanced the CKD, the greater the increase in CV risk. In effect, this decreases the time taken to cross the CV event threshold (denoted by the leftward shift from A, B). AKI acute kidney injury, CAD coronary artery disease, CaReMe cardio-renal-metabolic, CKD chronic kidney disease, CV cardiovascular, ESKD end-stage kidney disease, HK hyperkalemia, HU hyperuricemia, T2D type 2 diabetes

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Cardiovascular Diabetology

ISSN: 1475-2840