Table 3 Cardiovascular events of study subjects with anti-hypertensive medications according to BP and age categories
Clinical event |  < 120/ < 70 mmHg | 120–129/70–79 mmHg | 130–139/80–89 mmHg | 140–149/90–99 mmHg |  ≥ 150/ ≥ 100 mmHg |
|---|---|---|---|---|---|
Total | |||||
 Events | 397 | 2901 | 5606 | 3519 | 2145 |
 Person-years | 25,355 | 195,990 | 389,630 | 20,951 | 97,809 |
 Incidence (events/100,000 person-years) | 1566 | 1480 | 1439 | 16,796 | 2193 |
 Adjusted HR (95% CI) | 0.95 (0.85–1.05) | 0.97 (0.93–1.02) | Ref | 1.11 (1.06–1.16) | 1.29 (1.23–1.36) |
 < 50 years | |||||
 Events | 21 | 214 | 511 | 269 | 136 |
 Person-years | 3985 | 35,306 | 80,961 | 38,353 | 13,671 |
 Incidence (events/100,000 person-years) | 527 | 606 | 631 | 701 | 995 |
 Adjusted HR (95% CI) | 0.89 (0.57–1.38) | 0.97 (0.82–1.14) | Ref | 1.11 (0.95–1.28) | 1.58 (1.30–1.91) |
50–59 years | |||||
 Events | 78 | 586 | 1285 | 738 | 342 |
 Person-years | 7829 | 63,159 | 127,672 | 62,997 | 25,614 |
 Incidence (events/100,000 person-years) | 996 | 928 | 1006 | 1171 | 1335 |
 Adjusted HR (95% CI) | 0.97 (0.77–1.22) | 0.91 (0.82–1.00) | Ref | 1.16 (1.06–1.27) | 1.28 (1.13–1.44) |
60–69 years | |||||
 Events | 151 | 1255 | 2231 | 1450 | 928 |
 Person-years | 8827 | 68,351 | 128,304 | 74,550 | 37,595 |
 Incidence (events/100,000 person-years) | 1711 | 1836 | 1739 | 1945 | 2468 |
 Adjusted HR (95% CI) | 0.95 (0.80–1.12) | 1.05 (0.98–1.13) | Ref | 1.10 (1.03–1.18) | 1.37 (1.27–1.48) |
≥ 70 years | |||||
 Events | 147 | 846 | 1579 | 1062 | 739 |
 Person-years | 4713 | 29,172 | 52,691 | 33,611 | 20,927 |
 Incidence (events/100,000 person-years) | 3119 | 2900 | 2997 | 3160 | 3531 |
 Adjusted HR (95% CI) | 1.00 (0.85–1.19) | 0.95 (0.87–1.03) | Ref | 1.05 (0.97–1.14) | 1.15 (1.05–1.25) |