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Table 3 Cardiovascular events of study subjects with anti-hypertensive medications according to BP and age categories

From: Blood pressure levels and cardiovascular risk according to age in patients with diabetes mellitus: a nationwide population-based cohort study

Clinical event  < 120/ < 70 mmHg 120–129/70–79 mmHg 130–139/80–89 mmHg 140–149/90–99 mmHg  ≥ 150/ ≥ 100 mmHg
Total
 Events 397 2901 5606 3519 2145
 Person-years 25,355 195,990 389,630 20,951 97,809
 Incidence (events/100,000 person-years) 1566 1480 1439 16,796 2193
 Adjusted HR (95% CI) 0.95 (0.85–1.05) 0.97 (0.93–1.02) Ref 1.11 (1.06–1.16) 1.29 (1.23–1.36)
 < 50 years
 Events 21 214 511 269 136
 Person-years 3985 35,306 80,961 38,353 13,671
 Incidence (events/100,000 person-years) 527 606 631 701 995
 Adjusted HR (95% CI) 0.89 (0.57–1.38) 0.97 (0.82–1.14) Ref 1.11 (0.95–1.28) 1.58 (1.30–1.91)
50–59 years
 Events 78 586 1285 738 342
 Person-years 7829 63,159 127,672 62,997 25,614
 Incidence (events/100,000 person-years) 996 928 1006 1171 1335
 Adjusted HR (95% CI) 0.97 (0.77–1.22) 0.91 (0.82–1.00) Ref 1.16 (1.06–1.27) 1.28 (1.13–1.44)
60–69 years
 Events 151 1255 2231 1450 928
 Person-years 8827 68,351 128,304 74,550 37,595
 Incidence (events/100,000 person-years) 1711 1836 1739 1945 2468
 Adjusted HR (95% CI) 0.95 (0.80–1.12) 1.05 (0.98–1.13) Ref 1.10 (1.03–1.18) 1.37 (1.27–1.48)
≥ 70 years
 Events 147 846 1579 1062 739
 Person-years 4713 29,172 52,691 33,611 20,927
 Incidence (events/100,000 person-years) 3119 2900 2997 3160 3531
 Adjusted HR (95% CI) 1.00 (0.85–1.19) 0.95 (0.87–1.03) Ref 1.05 (0.97–1.14) 1.15 (1.05–1.25)
  1. HR, hazard ratio; CI, confidence interval. BP, blood pressure