| DM (-) CKD (-) | DM ( +) CKD (-) | DM (-) CKD ( +) | DM ( +) CKD ( +) | Ptrend | |||
---|---|---|---|---|---|---|---|---|
n = 10,513 | HR (95% CI) | HR (95% CI) | n = 1332 | HR (95% CI) | n = 838 | HR (95% CI) | ||
All-cause mortality or New Q-wave MI | 330 (3.1%) | 1.00 (Ref) | 1.32 (1.07–1.61) | 92 (6.9%) | 1.54 (1.21–2.49) | 80 (9.5%) | 1.91 (1.47–2.49) |  < 0.001 |
 All-cause mortality | 226 (2.1%) | 1.00 (Ref) | 1.37 (1.08–1.75) | 74 (5.6%) | 1.67 (1.27–2.81) | 67 (8%) | 2.09 (1.55–2.81) |  < 0.001 |
 New Q-wave MI | 108 (1%) | 1.00 (Ref) | 1.29 (0.9–1.86) | 19 (1.4%) | 1.19 (0.72–2.3) | 13 (1.6%) | 1.26 (0.69–2.3) | 0.257 |
Stroke | 78 (0.7%) | 1.00 (Ref) | 1.86 (1.28–2.71) | 18 (1.4%) | 1.17 (0.68–3.48) | 19 (2.3%) | 2.04 (1.19–3.48) | 0.013 |
MI | 273 (2.6%) | 1.00 (Ref) | 1.48 (1.18–1.85) | 52 (3.9%) | 1.61 (1.18–3.49) | 53 (6.3%) | 2.54 (1.85–3.49) | 0.001 |
Any Revascularization | 917 (8.7%) | 1.00 (Ref) | 1.26 (1.11–1.43) | 129 (9.7%) | 1.17 (0.96–1.91) | 113 (13.5%) | 1.55 (1.26–1.91) |  < 0.001 |
 TVR | 466 (4.4%) | 1.00 (Ref) | 1.5 (1.27–1.78) | 71 (5.3%) | 1.28 (0.99–2.37) | 67 (8.0%) | 1.8 (1.38–2.37) |  < 0.001 |
Definite stent thrombosis | 82 (0.8%) | 1.00 (Ref) | 1.08 (0.69–1.7) | 13 (1.0%) | 1.43 (0.78–2.23) | 6 (0.7%) | 0.94 (0.4–2.23) | 0.569 |
MACE | 394 (3.7%) | 1.00 (Ref) | 1.43 (1.19–1.71) | 101 (7.6%) | 1.4 (1.11–2.42) | 93 (11.1%) | 1.9 (1.49–2.42) |  < 0.001 |
POCE | 1242 (11.8%) | 1.00 (Ref) | 1.3 (1.17–1.45) | 219 (16.4%) | 1.3 (1.12–2.06) | 194 (23.2%) | 1.75 (1.49–2.06) |  < 0.001 |
NACE | 1360 (12.9%) | 1.00 (Ref) | 1.27 (1.15–1.41) | 245 (18.4%) | 1.29 (1.12–2.03) | 213 (25.4%) | 1.74 (1.49–2.03) |  < 0.001 |
BARC 3 or 5 bleeding | 188 (1.8%) | 1.00 (Ref) | 1.05 (0.78–1.41) | 44 (3.3%) | 1.18 (0.83–2.39) | 37 (4.4%) | 1.64 (1.12–2.39) | 0.02 |
 BARC 5 bleeding | 27 (0.3%) | 1.00 (Ref) | 0.51 (0.2–1.3) | 8 (0.6%) | 1.16 (0.5–2.09) | 5 (0.6%) | 0.71 (0.24–2.09) | 0.704 |
 BARC 3 bleeding | 173 (1.6%) | 1.00 (Ref) | 1.12 (0.83–1.52) | 41 (3.1%) | 1.22 (0.85–2.71) | 35 (4.2%) | 1.84 (1.25–2.71) | 0.005 |
   BARC 3a bleeding | 77 (0.7%) | 1.00 (Ref) | 1.31 (0.85–2.01) | 25 (1.9%) | 1.64 (1.02–2.63) | 13 (1.6%) | 1.42 (0.76–2.63) | 0.054 |
   BARC 3b bleeding | 74 (0.7%) | 1.00 (Ref) | 1.01 (0.62–1.64) | 17 (1.3%) | 1.29 (0.73–3.71) | 14 (1.7%) | 2.02 (1.1–3.71) | 0.043 |
   BARC 3c bleeding | 38 (0.4%) | 1.00 (Ref) | 0.78 (0.37–1.65) | 3 (0.2%) | 0.38 (0.11–4.56) | 10 (1.2%) | 2.11 (0.98–4.56) | 0.524 |
BARC 2 bleeding | 489 (4.7%) | 1.00 (Ref) | 1 (0.83–1.21) | 82 (6.2%) | 1.07 (0.84–1.52) | 54 (6.4%) | 1.14 (0.85–1.52) | 0.388 |
BARC 2, 3 or 5 bleeding | 647 (6.2%) | 1.00 (Ref) | 1.01 (0.86–1.19) | 118 (8.9%) | 1.11 (0.9–1.62) | 84 (10%) | 1.27 (1–1.62) | 0.063 |