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Table 2 Baseline characteristics and outcomes of patients by GA categories

From: High glycated albumin is an independent predictor of low response to clopidogrel in ACS patients: a cross-sectional study

 

GA ≤ 15.5% (n = 609)

GA > 15.5% (n = 412)

P value

Male, m (%)

465 (76.4%)

287 (69.7%)

0.017

Age, y

58.4 ± 10.0

63.0 ± 10.1

0.000

BMI, kg/m2

26.0 ± 3.3

25.6 ± 3.1

0.126

Medical history, n, (%)

 Diabetes mellitus

73 (12.0%)

287 (69.7%)

0.000

 Hypertension

386 (63.4%)

282 (68.4%)

0.095

 Previous stroke

62 (10.2%)

51 (12.4%)

0.272

 Previous myocardial infarction

40 (6.6%)

37 (9.0%)

0.152

 Previous CABG

2 (0.3%)

6 (1.5%)

0.067

 Previous PCI

50 (8.2%)

26 (6.3%)

0.257

Presentations of ACS

  

0.319

 Unstable angina

555 (91.1%)

372 (90.3%)

 

 Non-STEMI

23 (3.8%)

23 (5.6%)

 

 STEMI

31 (5.1%)

17 (4.1%)

 

Current or previous smoking, n (%)

339 (55.7%)

218 (52.9%)

0.386

Baseline laboratory evaluation

 PLT, × 109/L

220.8 ± 56.6

212.0 ± 60.2

0.019

 TC, mmol/L

3.9 ± 1.0

3.9 ± 0.9

0.342

 LDL-C, mmol/L

2.3 ± 0.8

2.2 ± 0.7

0.356

 HDL-C, mmol/L

1.1 ± 0.2

1.1 ± 0.3

0.875

 TGs, mmol/L

1.6 ± 0.9

1.5 ± 1.0

0.451

 Creatinine, μmol/L

71.0 ± 14.4

70.7 ± 17.2

0.734

Glucose indices

 Fasting glucose, mmol/L

5.4 ± 1.6

7.5 ± 2.4

0.000

 HbA1c, %

5.9 ± 0.6

7.4 ± 1.4

0.000

 HOMA-IR

2.1 (1.6–3.1)

3.3 (1.9–4.9)

0.000

Antiplatelet responsiveness to clopidogrel

 Responders to clopidogrel

459 (75.4%)

273 (66.3%)

0.002

 ADPi

45.4 ± 25.4

39.7 ± 23.8

0.000

 MAADP

35.2 ± 14.5

39.0 ± 13.9

0.000

  1. BMI body mass index, CABG coronary artery bypass graft, PCI percutaneous coronary intervention, non-STEMI non-ST-segment elevation myocardial infarction, STEMI ST-segment elevation myocardial infarction, PLT platelet count, TC total cholesterol, LDL-C low-density lipoprotein-cholesterol, HDL-C high-density lipoprotein-cholesterol, TGs triglycerides, HbA1c hemoglobin A1c, HOMA-IR homeostatic model assessment for insulin resistance, ADPi ADP-induced platelet inhibition rate, MAADP the maximum amplitude of ADP-induced platelet-fibrin clot strength