Incidence of idiopathic cardiomyopathy in patients with type 2 diabetes in Taiwan: age, sex, and urbanization status-stratified analysis

Table 4 Overall and urbanization- and sex-specific incidence densities and relative hazards of idiopathic cardiomyopathy (ICD9 = 425.4; ICD10 = I42.0) in the diabetic and control groups. (Fine and Gray's method)

Variables^a	Control group				Diabetic group				Crude HR^b	Adjusted HR^b,f
Variables^a	No. of patients	No. of events	Person-years	ID^b (per 10,000 patient-years)	No. of patients	No. of events	Person-years	ID^b (per 10,000 patient-years)	Crude HR^b	Adjusted HR^b,f
Men
Urban	190,969	325	1,737,479	1.87	187,691	591	1,661,658	3.56	1.86 (1.62–2.13)	1.49 (1.27–1.74)^c
Rural	76,189	160	688,093	2.33	79,468	311	694,967	4.48	1.86 (1.54–2.25)	1.55 (1.26–1.93)^c
Total	267,161	485	2,425,602	2.00	267,163	902	2,356,651	3.83	1.86 (1.67–2.08)	1.51 (1.33–1.72)^d
Women
Urban	151,148	164	1,397,475	1.17	144,610	325	1,307,333	2.49	2.08 (1.72–2.51)	1.63 (1.32–2.02)^c
Rural	55,955	93	515,813	1.80	62,495	225	562,198	4.00	2.15 (1.69–2.74)	2.03 (1.55–2.66)^c
Total	207,105	257	1,913,308	1.34	207,105	550	1,869,531	2.94	2.14 (1.85–2.48)	1.79 (1.52–2.12)^d
Overall	474,266	742	4,338,910	1.71	474,268	1452	4,226,182	3.44	1.96 (1.79–2.14)	1.60 (1.45–1.77)^e

^aInconsistency in the total numbers of patients and person-years between the total population and those summed for population from urban and rural areas was due to missing information of urbanization status for some study subjects
^bBased on Poisson assumption, ID incidence density, HR hazard ratio
^cBased on Cox proportional hazard regression with adjustment for age; status of ischemic heart disease, hypertensive disease, rheumatic heart disease, valvular heart disease, congenital heart disease, acute myocarditis, stroke, obesity, and hyperlipidemia; and antihypertensive medications use
^dBased on Cox proportional hazard regression with adjustment for age and urbanization status; status of ischemic heart disease, hypertensive disease, rheumatic heart disease, valvular heart disease, congenital heart disease, acute myocarditis, stroke, obesity, and hyperlipidemia; and antihypertensive medications use
^eBased on Cox proportional hazard regression with adjustment for age, sex, and urbanization status; status of ischemic heart disease, hypertensive disease, rheumatic heart disease, valvular heart disease, congenital heart disease, acute myocarditis, stroke, obesity, and hyperlipidemia; and antihypertensive medications use
^fp value for the interaction of diabetes and sex, diabetes and urbanization in males, and diabetes and urbanization in females were 0.2088, 0.8646, and 0.6166, respectively

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