Incidence of idiopathic cardiomyopathy in patients with type 2 diabetes in Taiwan: age, sex, and urbanization status-stratified analysis

Table 3 Overall and age- and sex-specific incidence densities and relative hazards of idiopathic cardiomyopathy (ICD9 = 425.4; ICD10 = I42.0) in the diabetic and control groups (Fine and Gray's method)

Variables	Control group				Diabetic group				Crude HR^a	Adjusted HR^a,e
Variables	No. of patients	No. of events	Person-years	ID^a (per 10,000 patient-years)	No. of patients	No. of events	Person-years	ID^a (per 10,000 patient-years)	Crude HR^a	Adjusted HR^a,e
Men
< 45	54,958	40	500,374	0.80	54,958	176	490,078	3.59	4.34 (3.08–6.13)	3.35 (2.21–5.06)^b
45–64	152,390	253	1,402,959	1.80	152,390	485	1,368,095	3.55	1.93 (1.66–2.25)	1.52 (1.27–1.81)^b
> 64	59,813	192	522,269	3.68	59,815	241	498,478	4.83	1.26 (1.04–1.52)	1.14 (0.92–1.40)^b
Total	267,161	485	2,425,602	2.00	267,163	902	2,356,651	3.83	1.86 (1.67–2.08)	1.51 (1.33–1.72)^c
Women
< 45	30,914	9	282,840	0.32	30,914	58	280,289	2.07	6.45 (3.2–13.02)	3.48 (1.60–7.56)^b
45–64	116,479	93	1,088,808	0.85	116,479	276	1,072,278	2.57	2.94 (2.33–3.73)	2.21 (1.67–2.92)^b
> 64	59,712	155	541,660	2.86	59,712	216	516,964	4.18	1.40 (1.14–1.72)	1.39 (1.11–1.74)^b
Total	207,105	257	1,913,308	1.34	207,105	550	1,869,531	2.94	2.14 (1.85–2.48)	1.79 (1.52–2.12)^c
Overall	474,266	742	4,338,910	1.71	474,268	1452	4,226,182	3.44	1.96 (1.79–2.14)	1.60 (1.45–1.77)^d

^aBased on Poisson assumption, ID incidence density, HR hazard ratio
^bBased on Cox proportional hazard regression with adjustment for urbanization status; status of ischemic heart disease, hypertensive disease, rheumatic heart disease, valvular heart disease, congenital heart disease, acute myocarditis, stroke, obesity, and hyperlipidemia; and antihypertensive medications use
^cBased on Cox proportional hazard regression with adjustment for age and urbanization status; status of ischemic heart disease, hypertensive disease, rheumatic heart disease, valvular heart disease, congenital heart disease, acute myocarditis, stroke, obesity, and hyperlipidemia; and antihypertensive medications use
^dBased on Cox proportional hazard regression with adjustment for age, sex and urbanization status; status of ischemic heart disease, hypertensive disease, rheumatic heart disease, valvular heart disease, congenital heart disease, acute myocarditis, stroke, obesity, and hyperlipidemia; and antihypertensive medications use
^ep values for the interaction of diabetes and sex, diabetes and age in males, and diabetes and age in females were 0.2088, < 0.0001, and < 0.0001, respectively

ISSN: 1475-2840