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Table 2 10-year CVD risk prediction according to Steno type 1 Risk Engine (ST1RE) in a cohort of adults aged < 35 or ≥ 35 years in whom the CVD risk was classified according to 2019 ESC criteria (n = 532)

From: Evaluation of cardiovascular risk in adults with type 1 diabetes: poor concordance between the 2019 ESC risk classification and 10-year cardiovascular risk prediction according to the Steno Type 1 Risk Engine

CVD risk classification according to 2019 ESC guidelines 10-year CVD risk stratification predicted according to ST1RE
  Very high risk High risk Moderate risk
Patients < 35 years (n = 316)
 Very high risk n = 96 0 (0) 1 (1) 95 (99)
  Target organ damage n = 26 0 (0) 0 (0) 26 (100)
  Three or more risk factors n = 5  0 (0) 0 (0) 5 (100)
  Early onset T1D of long duration (> 20 years) n = 50  0 (0) 0 (0) 50 (100)
  Two or more among the above criteria n = 15 0 (0) 1 (6.7) 14 (93.3)
 High risk n = 197 0 (0) 0 (0) 197 (100)
 Moderate risk n = 23 0 (0) 0 (0) 23 (100)
Patients ≥ 35 years (n = 216)
 Very high risk n = 142  17 (12) 41 (28.9) 84 (59.1)
  Target organ damage n = 23  2 (8.7) 4 (17.4) 17 (73.9)
  Three or more risk factors n = 49  4 (8.2) 14 (28.6) 31 (63.2)
  Early onset T1D of long duration (> 20 years) n = 10 0 (0) 3 (30) 7 (70)
  Two or more among the above criteria n = 60 11 (18.3) 20 (33.3) 29 (48.4)
 High risk n = 74 0 (0) 6 (8.1) 68 (91.9)
 Moderate risk n = 0 0 (0) 0 (0) 0 (0)
  1. Data are expressed as number (n) and percentage (%). The analysis was performed in 532 patients since 22 patients had a previous CVD and 20 patients had some missing data
  2. Target organ damage included proteinuria, eGFR < 30 ml/min/1.73 m2, left ventricular hypertrophy, or retinopathy
  3. CVD risk factors were: age > 35 years, hypertension, hypercholesterolemia, smoking, obesity