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Table 2 10-year CVD risk prediction according to Steno type 1 Risk Engine (ST1RE) in a cohort of adults aged < 35 or ≥ 35 years in whom the CVD risk was classified according to 2019 ESC criteria (n = 532)

From: Evaluation of cardiovascular risk in adults with type 1 diabetes: poor concordance between the 2019 ESC risk classification and 10-year cardiovascular risk prediction according to the Steno Type 1 Risk Engine

CVD risk classification according to 2019 ESC guidelines

10-year CVD risk stratification predicted according to ST1RE

 

Very high risk

High risk

Moderate risk

Patients < 35 years (n = 316)

 Very high risk n = 96

0 (0)

1 (1)

95 (99)

  Target organ damage n = 26

0 (0)

0 (0)

26 (100)

  Three or more risk factors n = 5 

0 (0)

0 (0)

5 (100)

  Early onset T1D of long duration (> 20 years) n = 50 

0 (0)

0 (0)

50 (100)

  Two or more among the above criteria n = 15

0 (0)

1 (6.7)

14 (93.3)

 High risk n = 197

0 (0)

0 (0)

197 (100)

 Moderate risk n = 23

0 (0)

0 (0)

23 (100)

Patients ≥ 35 years (n = 216)

 Very high risk n = 142 

17 (12)

41 (28.9)

84 (59.1)

  Target organ damage n = 23 

2 (8.7)

4 (17.4)

17 (73.9)

  Three or more risk factors n = 49 

4 (8.2)

14 (28.6)

31 (63.2)

  Early onset T1D of long duration (> 20 years) n = 10

0 (0)

3 (30)

7 (70)

  Two or more among the above criteria n = 60

11 (18.3)

20 (33.3)

29 (48.4)

 High risk n = 74

0 (0)

6 (8.1)

68 (91.9)

 Moderate risk n = 0

0 (0)

0 (0)

0 (0)

  1. Data are expressed as number (n) and percentage (%). The analysis was performed in 532 patients since 22 patients had a previous CVD and 20 patients had some missing data
  2. Target organ damage included proteinuria, eGFR < 30 ml/min/1.73 m2, left ventricular hypertrophy, or retinopathy
  3. CVD risk factors were: age > 35 years, hypertension, hypercholesterolemia, smoking, obesity