| Events (n) | Follow-up duration (person-years) | Incidence rate (per 1000 person-years) | Age- and sex- Adjusted HR (95% CI) | Multivariate-adjusted HR (95% CI) | |
---|---|---|---|---|---|---|
Model 1 | Model 2 | |||||
Stroke | ||||||
 VIM Q1 (n = 156061) | 6350 | 1185704.0 | 5.36 | 1 (Ref.) | 1 (Ref.) | 1 (Ref.) |
 VIM Q2 (n = 156058) | 6162 | 1191326.6 | 5.17 | 1.03 (0.99–1.07) | 1.03 (0.99–1.06) | 1.06 (1.02–1.09) |
 VIM Q3 (n = 156060) | 6214 | 1193013.0 | 5.21 | 1.08 (1.04–1.12) | 1.05 (1.02–1.09) | 1.10 (1.06–1.14) |
 VIM Q4 (n = 156058) | 6312 | 1191670.8 | 5.30 | 1.17 (1.13–1.21) | 1.10 (1.07–1.14) | 1.20 (1.16–1.24) |
  P for trend |  |  |  | < 0.001 | < 0.001 | < 0.001 |
Myocardial infarction | ||||||
 VIM Q1 (n = 156061) | 3859 | 1194006.5 | 3.23 | 1 (Ref.) | 1 (Ref.) | 1 (Ref.) |
 VIM Q2 (n = 156058) | 3899 | 1199121.6 | 3.25 | 1.06 (1.01–1.11) | 1.05 (1.00–1.10) | 1.07 (1.02–1.12) |
 VIM Q3 (n = 156060) | 3978 | 1200620.1 | 3.31 | 1.11 (1.07–1.16) | 1.09 (1.04–1.13) | 1.12 (1.07–1.17) |
 VIM Q4 (n = 156058) | 4096 | 1199009.4 | 3.42 | 1.21 (1.16–1.27) | 1.14 (1.09–1.20) | 1.20 (1.15–1.25) |
  P for trend |  |  | < 0.001 | < 0.001 | < 0.001 | |
All-cause mortality | ||||||
 VIM Q1 (n = 156061) | 10506 | 1205853.5 | 8.71 | 1 (Ref.) | 1 (Ref.) | 1 (Ref.) |
 VIM Q2 (n = 156058) | 10608 | 1211059.8 | 8.76 | 1.09 (1.06–1.119) | 1.08 (1.05–1.11) | 1.10 (1.07–1.13) |
 VIM Q3 (n = 156060) | 11181 | 1212864.1 | 9.22 | 1.19 (1.16–1.22) | 1.15 (1.12–1.18) | 1.17 (1.14–1.20) |
 VIM Q4 (n = 156058) | 12421 | 1211473.9 | 10.25 | 1.40 (1.36–1.44) | 1.29 (1.26–1.33) | 1.32 (1.29–1.36) |
  P for trend |  |  |  | < 0.001 | < 0.001 | < 0.001 |