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Table 3 Hazard ratios and 95% confidence intervals for myocardial infarction and stroke according to the metabolic syndrome component exposure score (sensitivity analysis excluding subjects on treatment with diabetes mellitus, hypertension and dyslipidemia)

From: Exposure-weighted scoring for metabolic syndrome and the risk of myocardial infarction and stroke: a nationwide population-based study

 

Myocardial Infarction

Stroke

Events (n)

Incidence ratea

Model 1

Model 2

Events (n)

Incidence ratea

Model 1

Model 2

0 (n = 264,176)

281

0.24

1(ref.)

1(ref.)

250

0.21

1(ref.)

1(ref.)

1 (n = 268,457)

383

0.32

1.15 (0.99, 1.34)

1.16 (0.99, 1.35)

290

0.24

0.96 (0.81, 1.14)

0.96 (0.81, 1.14)

2 (n = 250,345)

412

0.37

1.19 (1.02, 1.39)

1.21 (1.03, 1.41)

330

0.30

1.04 (0.88, 1.22)

1.03 (0.87, 1.22)

3 (n = 229,275)

433

0.43

1.26 (1.08, 1.47)

1.28 (1.10, 1.50)

404

0.40

1.25 (1.07, 1.47)

1.25 (1.06, 1.47)

4 (n = 213,530)

526

0.56

1.54 (1.33, 1.78)

1.58 (1.36, 1.83)

469

0.50

1.44 (1.24, 1.68)

1.43 (1.22, 1.68)

5 (n = 182,721)

451

0.56

1.47 (1.26, 1.71)

1.52 (1.30, 1.78)

442

0.55

1.50 (1.28, 1.75)

1.50 (1.28, 1.77)

6 (n = 156,233)

449

0.65

1.64 (1.41, 1.91)

1.72 (1.47, 2.01)

453

0.66

1.72 (1.47, 2.01)

1.74 (1.48, 2.05)

7 (n = 131,958)

480

0.83

2.05 (1.76, 2.38)

2.16 (1.85, 2.53)

446

0.77

1.97 (1.69, 2.31)

2.02 (1.71, 2.39)

8 (n = 114,510)

425

0.85

2.04 (1.75, 2.38)

2.18 (1.85, 2.57)

419

0.83

2.08 (1.78, 2.44)

2.16 (1.83, 2.56)

9 (n = 90,496)

404

1.02

2.44 (2.09, , 2.85)

2.63 (2.23, 3.11)

380

0.96

2.38 (2.03, 2.80)

2.52 (2.12, 2.99)

10 (n = 71,738)

351

1.12

2.65 (2.26, 3.11)

2.88 (2.43, 3.42)

345

1.10

2.70 (2.29, 3.19)

2.89 (2.42, 3.45)

11 (n = 55,777)

281

1.15

2.70 (2.29, 3.20)

2.96 (2.47, 3.55)

306

1.26

3.05 (2.57, 3.61)

3.28 (2.73, 3.94)

12 (n = 43,704)

318

1.67

3.87 (3.29, 4.56)

4.26 (3.56, 5.09)

290

1.52

3.66 (3.08, 4.34)

3.92 (3.25, 4.73)

13 (n = 29,989)

244

1.86

4.33 (3.64, 5.15)

4.79 (3.96, 5.80)

214

1.63

3.94 (3.28, 4.74)

4.26 (3.49, 5.21)

14 (n = 20,669)

206

2.29

5.29 (4.41, 6.35)

5.89 (4.82, 7.19)

194

2.15

5.19 (4.29, 6.27)

5.62 (4.56, 6.91)

15 (n = 13,867)

172

2.86

6.61 (5.45, 8.00)

7.37 (5.97, 9.11)

149

2.47

5.97 (4.86, 7.32)

6.44 (5.15, 8.04)

16 (n = 9246)

128

3.19

7.15 (5.79, 8.83)

7.99 (6.35, 10.06)

108

2.69

6.23 (4.96, 7.82)

6.61 (5.18, 8.45)

17 (n = 4643)

76

3.78

8.46 (6.56, 10.92)

9.55 (7.27, 12.54)

64

3.18

7.40 (5.61, 9.75)

8.01 (5.98, 10.73)

18 (n = 2437)

38

3.60

8.15 (5.80, 11.46)

9.21 (6.46, 13.12)

35

3.31

7.83 (5.49, 11.17)

8.34 (5.77, 12.05)

19 (n = 1324)

24

4.19

9.23 (6.08, 14.02)

10.42 (6.78, 16.04)

19

3.31

7.34 (4.60, 11.71)

7.67 (4.75, 12.38)

20 (n = 728)

21

6.72

15.37 (9.86, 23.96)

17.41 (11.02, 27.51)

20

6.36

15.18 (9.62, 23.94)

15.49 (9.69, 24.76)

P for trend

  

< 0.0001

< 0.0001

  

< 0.0001

< 0.0001

  1. aper 1 000 person-years
  2. Model 1: Adjusted for age, sex, alcohol consumption, smoking, regular exercise, income status
  3. Model 2: Adjusted for model 1 + baseline systolic blood pressure, waist circumference, fasting glucose, triglyceride and high-density lipoprotein-cholesterol levels
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Cardiovascular Diabetology

ISSN: 1475-2840