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Table 4 Clinical performance of the model to predict 10-year cardiovascular risk containing FRS and FRS + TyG-index models in the Population < 60 years (n = 6175): Tehran Lipid and Glucose Study

From: The impact of triglyceride-glucose index on incident cardiovascular events during 16 years of follow-up: Tehran Lipid and Glucose Study

 

FRS model*

HR (95% CI)

P-value

FRS + TyG-index

HR (95% CI)

P-value

Model components

 FRS

1.07 (1.06–1.07)

< 0.001

1.06 (1.05–1.06)

< 0.001

 TyG-index

–

 

1.42 (1.26–1.60)

< 0.001

Model predictive performance indexes

 C-index

0.789 (0.773-0.805)

<0.001

0.771 (0.752–0.789)

< 0.001

 IDI

–

–

0.001 (−0.004 to 0.007)

0.673

  1. FRS Framingham risk score, TyG-index Triglyceride-Glucose index, HR hazard ratio, CI confidence interval, C-index Harrell’s concordance statistic, IDI integrated discrimination improvement
  2. *FRS model: Framingham risk score model including age, gender, total cholesterol, high density lipoprotein cholesterol, systolic blood pressure, anti-hypertensive drugs, smoking, and type 2 diabetes
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Cardiovascular Diabetology

ISSN: 1475-2840