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Table 2 Comparison between the patients without significant coronary artery stenosis (CS) or with moderate (50–69%) or severe (≥ 70%) CS

From: Triglyceride glucose index for the detection of asymptomatic coronary artery stenosis in patients with type 2 diabetes

  Total No significant CS CS 50–69% CS  ≥ 70% P
Number 166 106 28 32  
Age (years) 58.9 ± 10.8 57.2 ± 10.7 60.9 ± 9.8 62.8 ± 11.0 0.020
Gender (M/F) 103/63 63/43 21/7 19/13 0.301
BMI (kg/m2) 24.8 ± 2.6 24.5 ± 2.7 24.6 ± 2.5 26.0 ± 2.1 0.019
Waist circumference (cm) 90.4 ± 11.3 88.8 ± 11.3 92.1 ± 11.7 94.0 ± 10.4 0.054
Systolic blood pressure (mmHg) 140.6 ± 22.4 130.3 ± 18.5 152.0 ± 18.3 165.0 ± 11.1  < 0.0001
Diastolic blood pressure (mmHg) 85.7 ± 13.8 80.3 ± 11.2 91.1 ± 14.9 98.8 ± 9.5  < 0.0001
Duration of diabetes (years) 4.00 [3.00–8.00] 3.00 [2.00–4.00] 7.00 [6.00–9.00] 11.50 [8.00–12.00]  < 0.0001
Practicing physical activity 43 (25.9) 30 (28.3) 10 (35.7) 3 (9.4) 0.043
Smoking 61 (36.7) 27 (25.5) 15 (53.6) 19 (59.4)  < 0.0001
Metabolic syndrome 109 (65.7) 60 (56.6) 17 (60.7) 32 (100.0)  < 0.0001
Total cholesterol (mg/dl) 221.2 ± 52.3 222.7 ± 53.3 225.5 ± 46.1 212.5 ± 54.8 0.562
Triglycerides (mg/dl) 228.7 ± 93.4 218.3 ± 94.3 233.6 ± 98.6 259.0 ± 80.4 0.091
HDL-cholesterol (mg/dl) 44.0 ± 10.6 45.2 ± 11.3 44.2 ± 10.8 40.0 ± 6.4 0.053
LDL-cholesterol (mg/dl) 134.3 ± 45.0 130.5 ± 44.9 143.2 ± 51.5 139.2 ± 39.0 0.330
Non-HDL cholesterol (mg/dl) 177.2 ± 51.9 177.5 ± 52.7 181.3 ± 47.7 172.5 ± 54.0 0.804
Fasting plasma glucose (mg/dl) 153.6 ± 46.8 147.0 ± 43.5 148.2 ± 53.3 180.2 ± 43.0 0.001
HbA1c (%) 7.9 ± 1.0 7.6 ± 0.8 7.9 ± 0.8 8.9 ± 1.1 0.000
TyG index 9.64 ± 0.63 9.56 ± 0.61 9.58 ± 0.71 9.97 ± 0.49 0.005
Insulin (mU/L) 22 [15–34] 21 [14–35] 20 [12–31] 30 [20–40] 0.092
HOMA-IR index 8.10 [4.65–13.93] 7.60 [4.33–12.83] 6.20 [2.95–11.90] 13.45 [7.48–17.53] 0.001
eGFR (mL/min/1.73m2) 85.3 ± 23.5 88.7 ± 26.0 80.2 ± 15.8 78.3 ± 18.2 0.040
Drug therapy
 Metformin 163 (98.2) 104 (98.1) 28 (100) 31 (96.9) 0.660
 Sulphonylurea 149 (89.8) 91 (85.8) 28 (100) 30 (93.8) 0.064
 Thiazolidinedione 1 (0.6) 1 (0.9) 0 (0) 0 (0) 0.752
 DPP-4 inhibitor 5 (3.0) 0 (0) 2 (7.1) 3 (9.4) 0.009
 α-glucosidase inhibitor 30 (18.1) 5 (4.7) 9 (32.1) 16 (50.0)  < 0.0001
 Insulin 3 (1.8) 0 (0) 2 (7.1) 1 (3.1) 0.034
 Antiplatelet 94 (56.6) 46 (43.4) 23 (82.1) 25 (78.1)  < 0.0001
 Statin 96 (57.8) 47 (44.3) 23 (82.1) 26 (81.2)  < 0.0001
  1. Data are expressed as mean ± SD, median (interquartile range) or number (%)
  2. Comparisons were performed using ANOVA or Kruskall-Wallis tests and chi square tests
  3. BMI body mass index, CS coronary stenosis, eGFR estimated glomerular filtration rate, HOMA-IR homeostatic model assessment of insulin resistance, M/F male/female, TyG index triglyceride glucose index