Skip to main content

Table 2 Comparison between the patients without significant coronary artery stenosis (CS) or with moderate (50–69%) or severe (≥ 70%) CS

From: Triglyceride glucose index for the detection of asymptomatic coronary artery stenosis in patients with type 2 diabetes

 

Total

No significant CS

CS 50–69%

CS  ≥ 70%

P

Number

166

106

28

32

 

Age (years)

58.9 ± 10.8

57.2 ± 10.7

60.9 ± 9.8

62.8 ± 11.0

0.020

Gender (M/F)

103/63

63/43

21/7

19/13

0.301

BMI (kg/m2)

24.8 ± 2.6

24.5 ± 2.7

24.6 ± 2.5

26.0 ± 2.1

0.019

Waist circumference (cm)

90.4 ± 11.3

88.8 ± 11.3

92.1 ± 11.7

94.0 ± 10.4

0.054

Systolic blood pressure (mmHg)

140.6 ± 22.4

130.3 ± 18.5

152.0 ± 18.3

165.0 ± 11.1

 < 0.0001

Diastolic blood pressure (mmHg)

85.7 ± 13.8

80.3 ± 11.2

91.1 ± 14.9

98.8 ± 9.5

 < 0.0001

Duration of diabetes (years)

4.00 [3.00–8.00]

3.00 [2.00–4.00]

7.00 [6.00–9.00]

11.50 [8.00–12.00]

 < 0.0001

Practicing physical activity

43 (25.9)

30 (28.3)

10 (35.7)

3 (9.4)

0.043

Smoking

61 (36.7)

27 (25.5)

15 (53.6)

19 (59.4)

 < 0.0001

Metabolic syndrome

109 (65.7)

60 (56.6)

17 (60.7)

32 (100.0)

 < 0.0001

Total cholesterol (mg/dl)

221.2 ± 52.3

222.7 ± 53.3

225.5 ± 46.1

212.5 ± 54.8

0.562

Triglycerides (mg/dl)

228.7 ± 93.4

218.3 ± 94.3

233.6 ± 98.6

259.0 ± 80.4

0.091

HDL-cholesterol (mg/dl)

44.0 ± 10.6

45.2 ± 11.3

44.2 ± 10.8

40.0 ± 6.4

0.053

LDL-cholesterol (mg/dl)

134.3 ± 45.0

130.5 ± 44.9

143.2 ± 51.5

139.2 ± 39.0

0.330

Non-HDL cholesterol (mg/dl)

177.2 ± 51.9

177.5 ± 52.7

181.3 ± 47.7

172.5 ± 54.0

0.804

Fasting plasma glucose (mg/dl)

153.6 ± 46.8

147.0 ± 43.5

148.2 ± 53.3

180.2 ± 43.0

0.001

HbA1c (%)

7.9 ± 1.0

7.6 ± 0.8

7.9 ± 0.8

8.9 ± 1.1

0.000

TyG index

9.64 ± 0.63

9.56 ± 0.61

9.58 ± 0.71

9.97 ± 0.49

0.005

Insulin (mU/L)

22 [15–34]

21 [14–35]

20 [12–31]

30 [20–40]

0.092

HOMA-IR index

8.10 [4.65–13.93]

7.60 [4.33–12.83]

6.20 [2.95–11.90]

13.45 [7.48–17.53]

0.001

eGFR (mL/min/1.73m2)

85.3 ± 23.5

88.7 ± 26.0

80.2 ± 15.8

78.3 ± 18.2

0.040

Drug therapy

 Metformin

163 (98.2)

104 (98.1)

28 (100)

31 (96.9)

0.660

 Sulphonylurea

149 (89.8)

91 (85.8)

28 (100)

30 (93.8)

0.064

 Thiazolidinedione

1 (0.6)

1 (0.9)

0 (0)

0 (0)

0.752

 DPP-4 inhibitor

5 (3.0)

0 (0)

2 (7.1)

3 (9.4)

0.009

 α-glucosidase inhibitor

30 (18.1)

5 (4.7)

9 (32.1)

16 (50.0)

 < 0.0001

 Insulin

3 (1.8)

0 (0)

2 (7.1)

1 (3.1)

0.034

 Antiplatelet

94 (56.6)

46 (43.4)

23 (82.1)

25 (78.1)

 < 0.0001

 Statin

96 (57.8)

47 (44.3)

23 (82.1)

26 (81.2)

 < 0.0001

  1. Data are expressed as mean ± SD, median (interquartile range) or number (%)
  2. Comparisons were performed using ANOVA or Kruskall-Wallis tests and chi square tests
  3. BMI body mass index, CS coronary stenosis, eGFR estimated glomerular filtration rate, HOMA-IR homeostatic model assessment of insulin resistance, M/F male/female, TyG index triglyceride glucose index