Table 3 MiRNA regulation during obesity, their function in the cardiovascular system and their potential targets in the redox system

miR-210

Unknown

–

EC apoptosis and atherosclerosis

[125]

ISCU 1,2

[124]

miR-21

Up

[130, 131]

Promotes ROS production

[132, 133]

SOD

[132, 133]

miR-551b

Up

[ [140]

Enhances ROS accumulation

[134, 135]

CAT, SOD

[134, 135]

miR-200c

Up

[142, 143]

EC apoptosis, ROS accumulation and senescence

[144, 145]

PRDX2

[144]

miR-17

Up

[151, 152]

EC dysfunction

[151, 152]

SOD, Gpx2

[149]

miR-23b

Up

[148]

EC dysfunction

[52, 146]

PRDX3

[147]

miR-29

Up

[154]

EC dysfunction, Cellular senescence

[155, 156]

ROS

[153]

miR-448

Down

[162, 163]

Attenuation of NOX2 induced-ROS accumulation

[161]

NOX2

[161]

miR-19b

Down

[166]

Attenuation of inflammation-induced EC apoptosis

[165]

p47phox

[164]

miR-25

Down

[170]

Prevent ROS production

[170]

NOX4

[170]

miR-146a

Up

[174]

EC inflammation

[173]

NOX4

[173]