Table 2 Outcomes in control subjects and diabetic patients, according to quartile of ANGPTL8 level
Outcomes— no. (%) | Control | p value | Diabetes | p value | ||||||
|---|---|---|---|---|---|---|---|---|---|---|
Q1 | Q2 | Q3 | Q4 | Q1 | Q2 | Q3 | Q4 | |||
Primary outcome | ||||||||||
Death | 2 (1.0) | 3 (1.6) | 5 (2.6) | 9 (4.7) | 0.10 | 6 (3.1) | 12 (6.2) | 13 (6.8) | 25 (13.0) | 0.002 |
Secondary outcomes | ||||||||||
| Â | 7 (3.6) | 10 (5.2) | 10 (5.2) | 17 (8.9) | 0.16 | 20 (10.4) | 21 (10.9) | 18 (9.4) | 32 (16.7) | 0.11 |
CVD death | 1 (0.5) | 1 (0.5) | 2 (1.0) | 6 (3.1) | 0.08 | 3 (1.6) | 9 (4.7) | 6 (3.1) | 13 (6.8) | 0.06 |
MI | 1 (0.5) | 2 (1.0) | 0 (0) | 7 (3.6) | 0.01 | 3 (1.6) | 6 (3.1) | 4 (2.1) | 11 (5.7) | 0.09 |
Stroke | 3 (1.6) | 7 (3.6) | 7 (3.6) | 6 (3.1) | 0.59 | 12 (6.3) | 8 (4.1) | 6 (3.1) | 8 (4.1) | 0.50 |
HF | 1 (0.5) | 1 (0.5) | 0 (0) | 1 (0.5) | 0.80 | 4 (2.1) | 2 (1.0) | 2 (1.0) | 4 (2.1) | 0.71 |
Renal dysfunction | 2 (1.0) | 0 (0) | 2 (1.0) | 3 (1.6) | 0.43 | 1 (0.5) | 4 (2.1) | 5 (2.6) | 13 (6.8) | 0.003 |