Skip to main content

Table 1 Characteristics of the study population according to glucose tolerance and linear correlational analysis with PWV

From: Ferritin modifies the relationship between inflammation and arterial stiffness in hypertensive patients with different glucose tolerance

Variables

All (n = 462)

HT/NGT (n = 271)

HT/IGT (n = 146)

HT/T2DM (n = 45)

p

PWV versus (r, p)

Gender, m/f

216/246

107/164

76/70

33/12

0.098

0.088 (p = 0.058)

Age, years

49.6 ± 12.2

49.5 ± 13.7

49.7 ± 10.1

49.5 ± 8.4

0.978

0.247 (p < 0.001)

BMI, kg/m2

28.9 ± 4.8

28.4 ± 4.4

29.3 ± 5.5

30.5 ± 4.7

0.014

0.014 (p = 0.772)

Fasting glucose, mg/dl

96.0 ± 14.1

91.0 ± 10.1

98.3 ± 13.0

118.8 ± 14.4

< 0.0001

0.068 (p = 0.143)

Fasting insulin, µU/ml

13.3 ± 6.6

12.5 ± 5.4

14.1 ± 7.4

15.4 ± 9.6

0.004

0.324 (p < 0.001)

MATSUDA

64.1 ± 45.3

70.9 ± 47.3

55.9 ± 40.9

49.6 ± 38.2

< 0.0001

− 0.425 (p < 0.001)

LDL cholesterol., mg/dl

127.1 ± 41.1

126.4 ± 40.8

127.1 ± 36.1

131.1 ± 55.5

0.775

− 0.034 (p = 0.467)

HDL cholesterol, mg/dl

51.9 ± 14.6

53.9 ± 14.6

49.8 ± 14.7

46.6 ± 11.7

0.001

− 0.100 (p = 0.032)

Triglycerides, mg/dl

128.9 ± 75.6

121.4 ± 66.1

138.1 ± 89.9

143.8 ± 74.1

0.037

0.063 (p = 0.177)

Smokers, n (%)

95 (20.6)

56 (20.7)

30 (20.5)

9 (20)

0.850

− 0.013 (p = 0.777)

Hemoglobin, g/dl

13.8 ± 1.2

13.8 ± 1.1

13.9 ± 1.2

13.4 ± 1.2

0.028

0.091 (p = 0.05)

Serum iron, µg/dl

80.7 ± 28.8

85.8 ± 31.3

76.3 ± 22.9

64.2 ± 21.8

< 0.0001

− 0.258 (p < 0.001)

Ferritin, ng/ml

106.6 ± 81.4

92.2 ± 78.6

120.7 ± 78.7

147.8 ± 85.9

< 0.0001

0.499 (p < 0.001)

Transferrin, g/l

2.6 ± 0.8

2.5 ± 0.6

2.7 ± 0.9

2.9 ± 0.9

< 0.0001

0.108 (p = 0.02)

hs-CRP, mg/l

2.6 ± 1.7

2.3 ± 1.6

2.8 ± 1.7

3.4 ± 1.8

< 0.0001

0.334 (p < 0.001)

TIBC, µg/dl

330.9 ± 87.2

314.8 ± 60.6

347.8 ± 110.6

373.2 ± 111.6

< 0.0001

0.086 (p = 0.064)

AST, U/l

23.9 ± 10.8

22.2 ± 9.3

25.2 ± 11.7

30.5 ± 13.2

< 0.0001

0.112 (p = 0.016)

ALT, U/l

27.1 ± 12.9

25.4 ± 12.1

28.3 ± 12.4

32.8 ± 17.2

0.001

0.084 (p = 0.07)

γGT, U/l

29.9 ± 15.7

27.2 ± 14.7

32.7 ± 16.6

36.8 ± 14.1

< 0.0001

0.095 (p = 0.041)

e-GFR, ml/min/1.73 m2

99.9 ± 23.2

102.4 ± 23.9

97.9 ± 20.4

91.6 ± 25.3

0.007

− 0.246 (p < 0.001)

  1. Data are mean and standard deviation, absolute and percent frequency
  2. H hypertensive, NGT normal glucose tolerance, T2DM type 2 diabetes mellitus, PWV pulse wave velocity, BMI body mass index, LDL low density lipoproteins, HDL high density lipoproteins, hs-CRP high sensitivity C reactive protein, TIBC transferrin iron binding capacity, AST aspartate aminotransferase, ALT alanine aminotransferase, γGT γ-glutamyltransferase, e-GFR estimated glomerular filtration rate
Back to article page

Cardiovascular Diabetology

ISSN: 1475-2840