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Table 4 Area under the curve for selected predictors of MACCE and mortality

From: Elevated levels of adiponectin associated with major adverse cardiovascular and cerebrovascular events and mortality risk in ischemic stroke

Predictors

MACCEa

Mortality

AUC (95%CI)

P

AUC (95%CI)

P

Adiponectin

0.71 (0.61–0.82)

–

0.73 (0.58-0.89)

–

Age

0.63 (0.55–0.72)

< 0.001

0.65 (0.56 –0.74)

< 0.001

CRP

0.65 (0.57 –0.75)

< 0.001

0.68 (0.59 –0.77)

< 0.001

NIHSS

0.73 (0.65 –0.84)

0.37

0.75 (0.66 –0.90)

0.42

Copeptin

0.73 (0.66 –0.85)

0.17

0.74 (0.64 –0.88)

0.28

NT-proBNP

0.68 (0.58 –0.77)

0.009

0.70 (0.58 –0.85)

0.011

Model Ib

0.76 (0.68 –0.88)

0.001

0.78 (0.69 –0.91)

< 0.001

Model IIc

0.79 (0.70 –0.90)

< 0.001

0.82 (0.71 –0.94)

< 0.001

Model IIId

0.77 (0.68 –0.86)

< 0.001

0.80 (0.69 –0.92)

< 0.001

Model IVe

0.81 (0.69 –0.93)

0.013f

0.84 (0.72 –0.96)

0.005f

  1. MACCE major adverse cardiovascular and cerebrovascular events, CI confidence interval, AUC Area Under Curve, NIHSS National Institutes of Health Stroke Scale, CRP C-reactive protein, NT-proBNP N-terminal fragment of precursor of B-type natriuretic peptide
  2. aMACCE was defined as CVD death, nonfatal myocardial infarction, nonfatal stroke, or coronary revascularization by percutaneous coronary intervention or coronary artery bypass grafting
  3. bModel I included NIHSS and Adiponectin
  4. cModel II included NIHSS, Adiponectin, Copeptin and NT-proBNP
  5. dModel III included NIHSS, CRP, age, Copeptin and NT-proBNP
  6. eModel IV included model III and Adiponectin
  7. fThe P value was compared with Model III
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Cardiovascular Diabetology

ISSN: 1475-2840