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Table 4 Risk of cardiovascular events across concordance/discordance groups stratified by diabetes status

From: Discordance between the triglyceride glucose index and fasting plasma glucose or HbA1C in patients with acute coronary syndrome undergoing percutaneous coronary intervention predicts cardiovascular events: a cohort study from China

Non-DMa

DMa

HbA1C/TyG†

HR (95%CI)

P value

HR (95%CI)

P value

Low/low (referent)

–

< 0.001

–

–

Low/High

1.91 (1.14–3.20)

0.014

2.10 (1.41–3.12)

< 0.001

High/Low

1.54 (0.90–2.62)

0.116

1.88 (1.26–2.81)

0.002

High/High

3.22 (2.02–5.16)

< 0.001

2.79(1.98–3.93)

< 0.001

FPG/TyG†

HR (95%CI)

P value

HR (95%CI)

P value

Low/low (referent)

–

< 0.001

–

–

Low/High

1.73 (1.23–2.45)

0.002

1.62 (1.01–2.62)

0.047

High/Low

0.40 (0.06–2.93)

0.369

1.4 3 (0.87–2.34)

0.161

High/High

3.56 (1.65–7.66)

0.001

1.99 (1.36–2.91)

< 0.001

  1. FPG fasting plasma glucose, HbA1C Glycosylated haemoglobin, TyG triglyceride glucose, HR hazard ratio, CI confidence interval
  2. †Different cutoff values were used by diabetes status. In non-DM group: Median HbA1C: 5.8%, median FBG: 5.52 mmol/L, median TyG: 8.74; In DM Group: guideling-guide HbA1C: 7.0%, equivalent percentage FPG: 7.11 mmol/L, equivalent percentage TyG:8.95
  3. aThe log-rank test and backward stepwise selection methods in a Cox proportional hazards regression model was performed; adjusted for age, sex, BMI, current smoker, hypertension, previous MI, previous stroke, previous PCI, previous CABG, non-HDL-C, lipid-lowering and antidiabetes medication use