Table 2 Baseline clinical, angiographic and procedural characteristics of propensity-matched patients with and without diabetes stratified according to medical therapy or successful CTO-PCI
| Â | Propensity-matched patients with diabetes | Propensity-matched patients without diabetes | ||||
|---|---|---|---|---|---|---|
Medical therapy | Successful PCI | P value | Medical therapy | Successful PCI | P value | |
(n = 270) | (n = 135) | (n = 464) | (n = 232) | |||
Age, years | 65.2 ± 4.7 | 64.6 ± 9.1 | 0.648 | 63.7 ± 10.9 | 63.2 ± 9.9 | 0.340 |
Male | 187 (69.3) | 100 (74.1) | 0.315 | 372 (80.5) | 184 (79.7) | 0.787 |
Smoking | 102 (37.8) | 55 (40.7) | 0.564 | 65 (14.1) | 26 (11.3) | 0.301 |
Hypertension | 197 (73.0) | 96 (71.1) | 0.694 | 302 (65.4) | 151 (65.4) | 1.000 |
Insulin-dependent DM | 106 (39.3) | 50 (37.0) | 0.665 | – | – | – |
Dyslipidemia | 213 (78.9) | 102 (75.6) | 0.447 | 330 (71.4) | 162 (70.1) | 0.722 |
Familial history o CAD | 23 (8.5) | 12 (8.9) | 0.900 | 118 (25.5) | 56 (24.2) | 0.710 |
Previous MI | 115 (42.6) | 59 (43.7) | 0.831 | 79 (17.1) | 40 (17.3) | 0.943 |
CKD | 33 (12.2) | 15 (11.1) | 0.744 | 37 (8.0) | 15 (6.5) | 0.475 |
Heart failure | 60 (22.2) | 30 (22.2) | 1.000 | 57 (12.3) | 21 (9.1) | 0.202 |
LVEF, % | 52.1 ± 10.9 | 52.4 ± 9.8 | 0.764 | 54.0 ± 8.3 | 54.9 ± 7.6 | 0.876 |
Baseline medication | ||||||
 Aspirin | 265 (98.1) | 132 (97.8) | 0.801 | 451 (97.6) | 224 (97.0) | 0.612 |
 Clopidogrel | 256 (94.8) | 128 (94.8) | 1.000 | 442 (95.7) | 227 (98.3) | 0.078 |
 Statin | 256 (94.8) | 131 (97.0) | 0.306 | 441 (95.5) | 221 (95.7) | 0.897 |
 β blocker | 196 (72.6) | 103 (76.3) | 0.424 | 369 (79.9) | 188 (81.4) | 0.636 |
 ACEI or ARB | 172 (63.7) | 85 (63.0) | 0.884 | 289 (62.6) | 142 (61.5) | 0.782 |
 One CTO lesion | 235 (87.0) | 115 (85.2) | 0.608 | 392 (84.8) | 192 (83.1) | 0.555 |
 Two CTO lesions | 33 (12.2) | 19 (14.1) | 0.599 | 63 (13.6) | 35 (15.2) | 0.589 |
 LAD | 85 (31.5) | 51 (37.8) | 0.206 | 175 (37.9) | 89 (38.5) | 0.868 |
 LCX | 73 (27.0) | 38 (28.1) | 0.813 | 120 (26.0) | 62 (26.8) | 0.807 |
 RCA | 143 (53.0) | 62 (45.9) | 0.182 | 232 (50.2) | 113 (48.9) | 0.747 |
 Multivessel disease | 221 (81.9) | 105 (77.8) | 0.329 | 360 (77.9) | 154 (66.7) | 0.001 |
 Proximal or mid | 170 (63.0) | 94 (69.6) | 0.184 | 341 (73.8) | 170 (73.6) | 0.159 |
CTO location | ||||||
 Blunt stump | 85 (31.5) | 33 (24.4) | 0.142 | 183 (39.6) | 74 (32.0) | 0.052 |
 Calcification | 32 (11.9) | 17 (12.6) | 0.829 | 71 (15.4) | 38 (16.5) | 0.712 |
 Bending > 45° | 117 (43.3) | 58 (43.0) | 0.943 | 206 (44.6) | 86 (37.2) | 0.064 |
 Length ≥ 20 mm | 160 (59.3) | 85 (63.0) | 0.472 | 306 (66.2) | 141 (61.0) | 0.178 |
 J-CTO score | 1.43 ± 1.16 | 1.41 ± 0.98 | 0.216 | 1.63 ± 1.11 | 1.44 ± 1.05 | 0.139 |
 SYNTAX score | 23.7 ± 8.3 | 22.4 ± 7.9 | 0.658 | 24.2 ± 8.5 | 22.7 ± 7.8 | 0.504 |