From: Glycemic variability: adverse clinical outcomes and how to improve it?
Types of metric | Computation or description | References |
---|---|---|
Long-term GV | ||
 Visit-to-visit measurements of HbA1c, FPG or PPG | Measures of SD or CV of HbA1c, FPG and PPG between sequential visits | [6] |
Short-term GV | ||
 SD | Variation around the mean blood glucose | [4] |
 CV | Magnitude of variability relative to mean blood glucose | [4] |
 MAGE | Mean differences from peaks to nadirs | [13] |
 CONGA | Difference between a current blood glucose reading and a reading taken hours earlier | [14] |
 MAG | Absolute differences between sequential readings divided by the time between the first and last blood glucose measurement | [2] |
 MODD | Absolute differences between two glucose values measured at the same time with a 24 h interval | [15] |
 AGP/IQR | Distribution of glucose data at a given timepoint and resulted as interquartile ranges | |
 LBGI/HBGI | Preceded by a log transform to render symmetric the skewed distribution of glucose values | |
 ADRR | Sum of the daily peak risks for hypoglycemia and hyperglycemia | [19] |
 TIR | Percentage of time per day within target glucose range (3.9–10.0 mmol/L) |