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Table 2 Baseline and changes in the coronary plaque characteristics

From: Quantitative assessment of coronary plaque volume change related to triglyceride glucose index: The Progression of AtheRosclerotic PlAque DetermIned by Computed TomoGraphic Angiography IMaging (PARADIGM) registry

  Total (n = 1143) TyG index tertiles P
I (lowest) 7.20–8.53 (n = 382) II 8.54–9.02 (n = 388) III (highest) 9.03–10.84 (n = 373)
At baseline
 Plaque volume (mm3)
  Total 44.1 (3.5–139.6) 30.8 (0.0–117.7) 47.2 (6.2 −160.4) 57.5 (8.4–154.3) < 0.001
  Fibrous 20.3 (0.8–59.1) 13.7 (0.0–49.7) 22.5 (2.9–67.3) 24.3 (3.8–64.4) 0.001
  Fibrous-fatty 3.5 (0.0–23.4) 1.4 (0.0–14.8) 3.6 (0.0–25.3) 6.1 (0.0–31.8) < 0.001
  Necrotic-core 0.0 (0.0–1.5) 0.0 (0.0–0.7) 0.0 (0.0–1.6) 0.1 (0.0–2.4) < 0.001
  Dense calcium 6.4 (0.0–38.1) 2.8 (0.0–33.5) 8.0 (0.0–41.2) 8.3 (0.0–36.5) 0.027
TAVnorm (mm3) 47.6 (2.6–151.5) 33.0 (0.0–122.3) 54.1 (7.4–192.3) 61.2 (9.5–165.6) 0.001
PAVtotal (%) 2.5 (0.1–7.7) 1.6 (0.0–6.1) 2.8 (0.4–8.8) 3.0 (0.5–8.1) 0.001
Annual change
 Plaque volume (mm3/year)
  Total 7.6 (0.5–22.2) 5.7 (0.0–20.2) 7.6 (0.5–23.5) 9.4 (1.4–27.7) 0.010
  Fibrous 1.9 (0.0–8.6) 1.1 (0.0–6.9) 1.9 (0.0–8.7) 2.8 (0.0–9.8) 0.022
  Fibrous-fatty 0.0 (-0.8–1.4) 0.0 (-0.5–0.9) 0.0 (-0.9–1.3) 0.0 (-1.0–2.3) 0.341
  Necrotic-core 0.0 (0.0–0.1) 0.0 (0.0–0.0) 0.0 (0.0–0.1) 0.0 (-0.1–0.1) 0.659
  Dense calcium 3.4 (0.1–11.7) 2.1 (0.0–8.7) 3.7 (0.3–12.1) 3.9 (0.4–13.3) 0.016
TAVnorm (mm3/year) 7.7 (0.4–24.4) 6.2 (0.0–19.9) 7.8 (0.5–25.4) 9.3 (1.7–31.2) 0.005
PAVtotal (%/year) 0.4 (0.0–1.2) 0.3 (0.0–0.9) 0.4 (0.0–1.3) 0.5 (0.1–1.4) 0.006
  1. Values are presented as median (interquartile range)
  2. PAVtotal total percent atheroma volume, TAVnorm normalized total atheroma volume, TyG triglyceride glucose
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Cardiovascular Diabetology

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