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Table 1 Baseline characteristics

From: The adipokine fatty-acid binding protein 4 and cardiac remodeling

 

All (n = 331)

Male (n = 236)

Female (n = 95)

p-value

Baseline characteristics

 Age, mean (sd)

63.1 (12.6)

62.4 (12.9)

64.6 (11.8)

0.156

 Hypertension, n (%)

246 (74.8)

176 (74.9)

70 (74.5)

1.00

 Diabetes, n (%)

57 (17.4)

47 (20.1)

10 (10.6)

0.06

 Active smoking, n (%)

59 (18.0)

42 (17.9)

17 (18.3)

< 0.001

 Coronary artery disease, n (%)

140 (42.6)

114 (48.5)

26 (27.7)

0.002

 Late gadolinium enhancement, n (%)

129 (39.1)

104 (44.1)

25 (26.6)

0.005

 Perfusion deficit, n (%)

65 (19.8)

49 (20.9)

16 (17.0)

0.525

 Atrial fibrillation, n (%)

66 (20.2)

48 (20.5)

18 (19.6)

0.969

 Body mass index (kg/m2), mean (sd)

27.5 (4.7)

27.7 (4.3)

27.0 (5.5)

0.21

 Height (cm), mean (sd)

174.4 (9.7)

178.4 (7.7)

164.4 (6.3)

< 0.001

 Weight (kg), mean (sd)

83.7 (16.6)

88.1 (15.2)

72.7 (14.6)

< 0.001

 Heart rate beats per min, mean (sd)

68 [12]

68 [12]

68 [12]

0.947

Cardiac magnet resonance imaging variables

 LVMI (g/m2), mean (sd)

44.5 (14.9)

47.6 (15.0)

36.6 (11.1)

< 0.001

 LVEF (%), mean (sd)

65.2 (6.5)

64.8 (6.7)

66.2 (5.9)

0.087

 LVEDD (mm), mean (sd)

49.6 (6.5)

51.0 (6.5)

46.3 (5.3)

< 0.001

 RVEDD (mm), mean (sd)

33.8 (6.8)

35.0 (6.5)

30.9 (6.9)

< 0.001

 RWT, mean (sd)

0.30 (0.12)

0.31 (0.13)

0.28 (0.09)

0.014

Laboratory results

 NT-proBNP (ng/L), median [IQR]

179.6 [76.9, 389.6]

179.3 [71.9, 416.5]

181.5 [81.1, 328.3]

0.592

 CRP (mg/dl), median [IQR]

0.2 [0.1, 0.4]

0.2 [0.1, 0.4]

0.2 [0.1, 0.4]

0.568

 hs-cTnT (ng/L), median [IQR]

9 [5, 16]

10 [6, 17]

8 [5, 14]

0.007

 Creatinin (µmol/L), mean (sd)

88.4 (61.9)

97.2 (70.7)

97.2 (26.5)

< 0.001

 eGFR (ml/min), mean (sd)

91.6 (32.7)

91.5 (32.0)

92.0 (34.5)

0.884

 FABP4 (ng/ml), median [IQR]

22.79 [13.84, 36.46]

18.36 [12.24, 31.33]

30.69 [20.96, 49.74]

0.001

  1. Baseline characteristic of 331 patients undergoing cardiac magnetic resonance imaging stratified by sex. Data presented as percentage, mean, or median
  2. Italic values indicate statistically significant differences between men and women (using the two-sided t test or Wilcoxon rank-sum test as appropriate), p-value < 0.05
  3. CRP, C- reactive protein; eGFR, estimated glomerular filtration rate; FABP4, Fatty-acid binding protein 4; hs-cTnT, cardiac high sensitivity troponin T; LVEDD, left ventricular end-diastolic diameter; LVEF, left ventricular ejection fraction; LVMI, left ventricular mass index; NT-proBNP, N-terminal pro B-type brain natriuretic peptid; RVEDD, right ventricular end-diastolic diameter; RWT, relative wall thickness