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Table 5 Associations of the TyG quintiles with HTN for different levels of age, BMI, eGFR

From: A high triglyceride glucose index is more closely associated with hypertension than lipid or glycemic parameters in elderly individuals: a cross-sectional survey from the Reaction Study

Variable

AGE < 55

OR (95% CI) P-value

(n = 16,438)

AGE ≥ 55, < 65

OR (95% CI) P-value

(n = 17,539)

AGE ≥ 65

OR (95% CI) P-value

(n = 9614)

P for interaction

BMI < 18.5

OR (95% CI) P-value

(n = 1281)

BMI ≥ 18.5, < 24

OR (95% CI) P-value

(n = 19,129)

BMI ≥ 24, < 28

OR (95% CI) P-value

(16,758)

BMI ≥ 28

OR (95% CI) P-value

(n = 6423)

P for interaction

eGFR < 90

OR (95% CI) P-value

(n = 9260)

eGFR ≥ 90

OR (95% CI) P-value

(n = 34,331)

P for interaction

N of HTN

4299

7764

6230

 

259

5902

8137

3995

 

6018

12,275

 

TC, mmol/L

   

0.4215

    

0.0339

  

0.2496

 < 1.7

1.0

1.0

1.0

 

1.0

1.0

1.0

1.0

 

1.0

1.0

 

 ≥ 1.7, < 2.3

1.23 (1.01, 1.48) 0.0348

1.16 (1.00, 1.34) 0.0470

1.44 (1.18, 1.76) 0.0004

 

1.05 (0.36, 3.03) 0.9323

1.25 (1.06, 1.48) 0.0081

1.28 (1.11, 1.49) 0.0009

1.19 (0.93, 1.51) 0.1660

 

1.46 (1.19, 1.79) 0.0003

1.19 (1.06, 1.34) 0.0026

 

 ≥ 2.3

1.13 (0.93, 1.36) 0.2135

1.21 (1.04, 1.40) 0.0111

1.15 (0.93, 1.42) 0.1872

 

0.10 (0.01, 1.25) 0.0740

0.98 (0.82, 1.17) 0.7960

1.27 (1.10, 1.46) 0.0014

1.36 (1.08, 1.72) 0.0085

 

1.24 (1.00, 1.54) 0.0477

1.17 (1.04, 1.31) 0.0069

 

TC, mmol/L

   

0.3512

    

0.5601

  

0.0882

 < 5.2

1.0

1.0

1.0

 

1.0

1.0

1.0

1.0

 

1.0

1.0

 

 ≥ 5.2, < 6.2

0.90 (0.77, 1.05) 0.1798

0.98 (0.86, 1.11) 0.7541

0.92 (0.78, 1.09) 0.3530

 

1.38 (0.69, 2.76) 0.3652

0.91 (0.79, 1.04) 0.1639

0.94 (0.82, 1.07) 0.3449

0.97 (0.78, 1.20) 0.7820

 

0.88 (0.74, 1.05) 0.1655

0.96 (0.87, 1.06) 0.4072

 

 ≥ 6.2

0.89 (0.72, 1.10) 0.2962

0.85 (0.72, 0.99) 0.0405

1.06 (0.85, 1.33) 0.6183

 

0.90 (0.36, 2.21) 0.8169

0.83 (0.70, 0.98) 0.0317

0.91 (0.77, 1.08) 0.2750

1.13 (0.85, 1.51) 0.3892

 

1.08 (0.86, 1.36) 0.5170

0.86 (0.76, 0.98) 0.0197

 

HDL-C, mmol/L

   

0.0368

    

0.8981

  

0.1921

 ≥ 1

1.0

1.0

1.0

 

1.0

1.0

1.0

1.0

 

1.0

1.0

 

 < 1

1.50 (1.23, 1.82) < 0.0001

1.34 (1.14, 1.57) 0.0004

1.03 (0.85, 1.26) 0.7484

 

1.28 (1.06, 1.54) 0.0091

1.30 (1.14, 1.48) < 0.0001

1.28 (1.10, 1.49) 0.0015

1.25 (0.98, 1.60) 0.0754

 

1.15 (0.94, 1.41) 0.1785

1.34 (1.19, 1.52) < 0.0001

 

LDL-C, mmol/L

   

0.4126

    

0.4256

  

0.1294

 < 3.4

1.0

1.0

1.0

 

1.0

1.0

1.0

1.0

 

1.0

1.0

 

 ≥ 3.4, < 4.1

1.09 (0.91, 1.30) 0.3674

0.99 (0.87, 1.14) 0.9010

0.93 (0.76, 1.12) 0.4351

 

1.99 (0.92, 4.30) 0.0798

0.98 (0.85, 1.14) 0.8071

0.96 (0.84, 1.11) 0.6107

1.09 (0.86, 1.39) 0.4817

 

0.89 (0.73, 1.08) 0.2271

1.04 (0.93, 1.15) 0.5173

 

 ≥ 4.1

0.97 (0.76, 1.23) 0.7791

0.98 (0.82, 1.16) 0.7966

1.20 (0.93, 1.55) 0.1623

 

1.06 (0.34, 3.26) 0.9206

1.00 (0.83, 1.21) 0.9911

0.96 (0.79, 1.15) 0.6439

1.27 (0.94, 1.73) 0.1246

 

1.17 (0.90, 1.52) 0.2487

0.98 (0.85, 1.12) 0.7628

 

TYG

   

0.4729

    

0.1052

  

0.1328

Q1

1.0

1.0

1.0

 

1.0

1.0

1.0

1.0

 

1.0

1.0

 

Q2

1.03 (0.83, 1.27) 0.7970

1.04 (0.87, 1.26) 0.6479

1.14 (0.89, 1.46) 0.2946

 

1.57 (0.79, 3.11) 0.1984

0.97 (0.81, 1.15) 0.6904

1.14 (0.93, 1.40) 0.2199

1.23 (0.84, 1.80) 0.2832

 

1.13 (0.88, 1.45) 0.3386

1.04 (0.91, 1.20) 0.5523

 

Q3

0.98 (0.79, 1.22) 0.8431

1.04 (0.86, 1.25) 0.7139

1.36 (1.07, 1.74) 0.0126

 

1.03 (0.42, 2.49) 0.9538

1.10 (0.93, 1.31) 0.2629

1.06 (0.87, 1.30) 0.5447

1.42 (0.98, 2.05) 0.0603

 

1.36 (1.06, 1.74) 0.0146

1.02 (0.89, 1.18) 0.7273

 

Q4

1.28 (1.02, 1.60) 0.0308

1.20 (1.00, 1.45) 0.0515

1.67 (1.30, 2.14) < 0.0001

 

1.68 (0.61, 4.58) 0.3122

1.21 (1.00, 1.45) 0.0496

1.34 (1.10, 1.64) 0.0042

1.85 (1.29, 2.65) 0.0009

 

1.72 (1.33, 2.21) < 0.0001

1.23 (1.07, 1.42) 0.0037

 

Q5

1.18 (0.93, 1.50) 0.1727

1.23 (1.00, 1.50) 0.0448

1.37 (1.05, 1.79) 0.0221

 

0.70 (0.14, 3.44) 0.6597

0.99 (0.80, 1.22) 0.9168

1.34 (1.09, 1.65) 0.0057

1.85 (1.28, 2.67) 0.0011

 

1.42 (1.08, 1.87) 0.0115

1.23 (1.06, 1.43) 0.0074

 

HbA1c,  %

   

0.5670

    

0.5270

  

0.8286

< 6.5

1.0

1.0

1.0

 

1.0

1.0

1.0

1.0

 

1.0

1.0

 

≥ 6.5

0.83 (0.61, 1.12) 0.2231

1.01 (0.83, 1.24) 0.9083

0.95 (0.75, 1.20) 0.6455

 

0.51 (0.15, 1.66) 0.2623

0.97 (0.76, 1.22) 0.7763

0.91 (0.74, 1.12) 0.3850

1.11 (0.81, 1.52) 0.5074

 

1.03 (0.81, 1.29) 0.8299

0.98 (0.84, 1.15) 0.7942

 

PBG, mmol/L

   

0.3262

    

0.9034

  

0.3296

< 11.1

1.0

1.0

1.0

 

1.0

1.0

1.0

1.0

 

1.0

1.0

 

≥ 11.1

0.89 (0.65, 1.21) 0.4452

1.15 (0.93, 1.41) 0.2000

1.15 (0.91, 1.44) 0.2434

 

0.73 (0.22, 2.47) 0.6141

1.15 (0.91, 1.46) 0.2374

1.10 (0.90, 1.35) 0.3652

1.09 (0.79, 1.50) 0.5916

 

1.24 (0.99, 1.55) 0.0598

1.08 (0.92, 1.26) 0.3633

 
  1. Adjusted for age; center; sex; history of CVDs; history of T2DM; hypoglycemic drugs; SBP; DBP; BMI; ALT; AST; WHR; eGFR; smoking habits; drinking habits
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Cardiovascular Diabetology

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