| Univariable analysis | Multivariable analysis | ||||
---|---|---|---|---|---|---|
HR | 95% CI | P-value | HR | 95% CI | P-value | |
Age (per 10 years) | 0.963 | 0.790–1.174 | 0.709 |  |  |  |
Sex (female) | 1.018 | 0.816–1.271 | 0.872 |  |  |  |
Low BMI (< 18.5 kg/m2) | 1.445 | 0.674–3.098 | 0.344 |  |  |  |
Hypertension | 0.740 | 0.502–1.091 | 0.128 | 0.767 | 0.516–1.140 | 0.189 |
Use of insulin | 1.394 | 0.978–1.987 | 0.066 | 1.147 | 0.789–1.668 | 0.472 |
Hypercholesterolemia | 1.182 | 0.834–1.675 | 0.346 |  |  |  |
End-stage renal disease | 1.725 | 1.095–2.718 | 0.019 | 1.719 | 1.074–2.753 | 0.024 |
Congestive heart failure | 1.225 | 0.598–2.506 | 0.579 |  |  |  |
Current smoker | 0.899 | 0.607–1.330 | 0.593 |  |  |  |
Coronary artery disease | 0.699 | 0.495–0.987 | 0.042 | 0.863 | 0.584–1.274 | 0.458 |
Previous history of stroke | 1.023 | 0.646–1.618 | 0.924 |  |  |  |
Previous history of bypass surgery | 1.846 | 0.754–4.518 | 0.180 | 1.598 | 0.637–4.009 | 0.318 |
Previous history of amputation | 1.547 | 0.872–2.745 | 0.136 | 1.172 | 0.649–2.118 | 0.598 |
Previous history of EVT | 2.230 | 1.406–3.537 | 0.001 | 2.333 | 1.455–3.740 | < 0.001 |
Critical limb ischemia | 1.194 | 0.839–1.700 | 0.325 |  |  |  |
HbA1c ≥ 7.0% | 1.458 | 1.001–2.123 | 0.049 | 1.473 | 1.005–2.160 | 0.047 |