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Table 1 Background of the patients with type 2 diabetes mellitus (n = 307)

From: Treatment with anagliptin, a DPP-4 inhibitor, decreases FABP4 concentration in patients with type 2 diabetes mellitus at a high risk for cardiovascular disease who are receiving statin therapy

 

Anagliptin

Sitagliptin

P

n (M/F)

148 (89/59)

159 (93/66)

0.77

Age (years)

68 ± 9

68 ± 9

0.91

Body mass index

26.7 ± 3.9

25.8 ± 3.6

0.04

Waist circumference (cm)

94.2 ± 11.1

92.7 ± 9.8

0.24

Smoking habit

71 (48)

92 (58)

0.08

Alcohol drinking habit

58 (39)

67 (42)

0.60

Diagnosis

 Hypertension

117 (79)

116 (73)

0.21

 Coronary artery disease

68 (46)

71 (45)

0.82

 Stroke

22 (15)

24 (15)

0.96

Medication

 Dipeptidyl peptidase-4 inhibitora

122 (82)

128 (81)

0.66

 Biguanide

74 (50)

71 (45)

0.35

 Thiazolidinedione

22 (15)

29 (18)

0.43

 α glucosidase inhibitor

19 (13)

27 (17)

0.31

 Sulfonylurea

41 (28)

32 (20)

0.12

 Glinide

7 (5)

2 (1)

0.09

 Sodium–glucose cotransporter 2 inhibitor

25 (17)

16 (10)

0.08

 Insulin

12 (8)

13 (8)

0.98

 Statin

148 (100)

159 (100)

–

 Strong statinb

118 (80)

121 (76)

0.44

 Ezetimibe

16 (11)

11 (7)

0.23

 Fibrate

9 (6)

7 (4)

0.51

 Eicosapentaenoic acid

16 (11)

13 (8)

0.43

 Angiotensin II receptor blocker

75 (51)

80 (50)

0.95

 Angiotensin-converting enzyme inhibitor

18 (12)

10 (6)

0.07

 Calcium channel blocker

72 (49)

68 (43)

0.30

 β blocker

35 (24)

38 (24)

0.96

 Diuretic

24 (16)

20 (13)

0.36

 Mineralocorticoid receptor antagonist

6 (4)

6 (4)

0.90

  1. Variables are expressed as number (%), mean ± SD or medians (interquartile ranges)
  2. aThe use before the study
  3. bIndicates atorvastatin, rosuvastatin and pitavastatin