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Table 2 Hazard ratios and 95% confidence intervals of ischemic stroke owing to pioglitazone use

From: Pioglitazone for primary stroke prevention in Asian patients with type 2 diabetes and cardiovascular risk factors: a retrospective study

VariablesIschemic stroke (n = 306)Crude HR (95% CI)p-valueAdjusted HR (95% CI)p-value
EventPYIR
Pioglitazone
 No17027,6826.141 (reference) 1 (reference) 
 Yes13629,2684.650.75 (0.60–0.90)**0.0090.78 (0.62–0.95)*0.03
  1. HR adjusted for age, sex, heart failure, arrhythmia, chronic kidney disease, hypertension, hyperlipidemia, hypertensive agents, lipid-lowering agents, anti-platelet agents, and oral glucose-lowering agents
  2. PY person-years, IR incidence rate, per 1000 person-years, HR hazard ratio, CI confidence interval, PY person-year, IR incidence rate, per 1000 person-years, HR hazard ratio, CI confidence interval
  3. * p < 0.05, ** p < 0.01