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Fig. 4 | Cardiovascular Diabetology

Fig. 4

From: Cardiovascular morbidity, diabetes and cancer risk among children and adolescents with severe obesity

Fig. 4

Cardiometabolic outcomes in adulthood of adolescents with severe versus mild obesity in national longitudinal cohorts. CHD: coronary heart disease; CVD: cardiovascular disease. Severe obesity and mild obesity were defined as BMI ≥ 35 and 30 ≤ BMI < 35 kg/m2, respectively. Cox proportional hazard models were used in all the studies. The horizontal axis is presented in the logarithmic scale. * The presented numbers of cases and participants were derived from the unadjusted models. †Swedish national cohort. Heart failure was determined as the first event of heart failure hospitalization. The reference groups were 18.5 < BMI < 20.0 kg/m2. Hazard ratios (HRs) were adjusted for age at entrance to the study, the year of entrance to the study, test center, comorbidities at baseline, parental education, systolic and diastolic blood pressure, muscle strength and fitness. HRs for heart failure were also adjusted for IQ level. HRs for cardiomyopathy were also adjusted for alcohol and substance use disorder. ‡Israeli national cohort. The reference group was 17.5 < BMI < 20.0 kg/m2. HRs were adjusted for age, birth year, sex, socioeconomic status, country of origin, education level and height

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