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Fig. 6 | Cardiovascular Diabetology

Fig. 6

From: Linagliptin, when compared to placebo, improves CD34+ve endothelial progenitor cells in type 2 diabetes subjects with chronic kidney disease taking metformin and/or insulin: a randomized controlled trial

Fig. 6

Arterial Stiffness Parameters. a Pulse wave velocity: at visit 1, the linagliptin group had lower PWV at a trend level of significance (p = 0.06). At visit 2, there was no difference (p = 0.91). At visit 3, the linagliptin group had significantly lower PWV (p = 0.03). The Linagliptin group increased PWV more from visit 1 to visit 2, and decreased more from visit 2 to 3, compared to the control group. b Pulse Wave Analysis: A similar pattern is seen here (comparing PWV with PWA). Error bars show the 95% confidence interval for the control group. There was not a significant effect of treatment group (p = 0.07), or of time (p = 0.98), but there was a significant group × time interaction (p = 0.02). The Linagliptin group increased more than placebo group from visit 1 to visit 2, but then rebounded back down more than the control group at visit 3

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Cardiovascular Diabetology

ISSN: 1475-2840