| Normal (n = 20) | Non-MetS (n = 23) | MetS (n = 30) |
---|---|---|---|
Baseline characteristics | |||
 Age (y) | 50.95 ± 10.185 | 54.85 ± 10.87 | 54.48 ± 9.61 |
 Male (n) | 10(50.0%) | 15(65.2%) | 16(53.3%) |
 High (cm) | 162.70 ± 7.08 | 162.85 ± 9.23 | 164.13 ± 7.29 |
 Weigh (kg) | 61.30 ± 5.96 | 58.52 ± 8.22 | 66.54 ± 8.55*β |
 BMI | 23.14 ± 1.49 | 22.03 ± 2.30 | 24.71 ± 3.05β |
 Systolic blood pressure (mmHg) | 119.45 ± 7.22 | 130.36 ± 16.86 | 132. ± 19.22* |
 Diastolic blood pressure (mmHg) | 78.75 ± 7.81 | 76.42 ± 7.67 | 80.09 ± 10.53 |
 Duration of diabetes (y) | – | 7.32 ± 7.24 | 7.90 ± 4.59 |
 Waist circumference (cm) | – | 83.33 ± 5.79 | 93.37 ± 1.05 |
Metabolic characteristics | |||
 HbA1c (%) | 5.38 ± 0.34 | 6.47 ± 2.87* | 6.75 ± 2.76* |
 GLU (mmol/l) | 5.07 ± 0.43 | 7.11 ± 5.12* | 5.70 ± 3.94 |
 TG (mmol/l) | 1.03 ± 0.27 | 1.14 ± 0.41 | 1.76 ± 1.64* |
 TC (mmol/l) | 4.30 ± 0.57 | 4.29 ± 0.86 | 4.59 ± 0.83 |
 HDL (mmol/l) | 1.31 ± 0.28 | 1.47 ± 0.34 | 1.23 ± 0.36 |
 LDL (mmol/l) | 2.71 ± 0.53 | 2.36 ± 0.73 | 2.70 ± 0.74 |
 Creatinine (μmol/l) | – | 66.20 ± 12.59 | 73.97 ± 22.15 |
 GFR (30 ml/min) | – | 99.84 ± 10.32 | 95.85 ± 19.17 |
 AST (U/l) | – | 23.00 ± 12.07 | 25.58 ± 15.82 |
 ALT (U/l) | – | 24.53 ± 8.94 | 23.04 ± 8.94 |
 Uric acid (μmol/l) | 340.00 ± 37.04 | 331.81 ± 60.49 | 359.88 ± 95.95 |
Medication, n (%) | |||
 Insulin | – | 7 (33%) | 10 (31%) |
 Metformin | – | 11 (52%) | 19 (59%) |
 Sulfonylurea | – | 2 (9%) | 9 (28%) |
 α-Glucosidase inhibitor | – | 5 (24%) | 16 (50%) |
 ACEI | – | 0 | 4 (13%) |
 Statin | – | 2 (9%) | 7 (22%) |