(N) | Unadjusted Hazard Ratioa | Adjusted Hazard Ratioa | ||||||
---|---|---|---|---|---|---|---|---|
HR | 95% CI | p-value | HR | 95% CI | HR | |||
Non-statin (5273) | 1.000 | Â | Â | 1.000 | Â | Â | ||
Atorvastatin (1071) | 1.791 | 1.598 | 2.009 | <  0.0001 | 1.942 | 1.661 | 2.269 | 1.942 |
 < 2 years (137) | 1.027 | 0.846 | 1.248 | 0.7853 | 0.989 | 0.8 | 1.222 | 0.989 |
 2–5 years (127) | 1.007 | 0.822 | 1.234 | 0.9448 | 1.005 | 0.791 | 1.277 | 1.005 |
 ≥ 5 years (807) | 1.907 | 1.563 | 2.327 | <  0.0001 | 1.83 | 1.487 | 2.252 | 1.83 |
Lovastatin (771) | 1.847 | 1.624 | 2.101 | <  0.0001 | 1.915 | 1.621 | 2.263 | 1.915 |
 < 2 years (103) | 1.07 | 0.862 | 1.328 | 0.5382 | 1.005 | 0.793 | 1.275 | 1.005 |
 2–5 years (92) | 1.113 | 0.885 | 1.401 | 0.3599 | 1.068 | 0.826 | 1.382 | 1.068 |
 ≥ 5 years (576) | 1.942 | 1.551 | 2.431 | <  0.0001 | 1.846 | 1.458 | 2.337 | <  0.0.0001 |
Pravastatin (391) | 1.662 | 1.39 | 1.986 | <  0.0001 | 1.758 | 1.429 | 2.164 | <  0.0001 |
 < 2 years (42) | 0.914 | 0.677 | 1.234 | 0.5582 | 0.981 | 0.706 | 1.363 | 0.9093 |
 2–5 years (50) | 1.256 | 0.946 | 1.666 | 0.1148 | 1.236 | 0.899 | 1.699 | 0.1911 |
 ≥ 5 years (299) | 1.779 | 1.335 | 2.371 | <  0.0001 | 1.633 | 1.211 | 2.203 | 0.0013 |
Rosuvastatin (243) | 1.723 | 1.381 | 2.15 | <  0.0001 | 1.932 | 1.511 | 2.471 | < 0.0001 |
 < 2 years (32) | 0.931 | 0.653 | 1.328 | 0.6927 | 0.826 | 0.547 | 1.247 | 0.3635 |
 2–5 years (30) | 1.727 | 1.198 | 2.491 | 0.0034 | 1.712 | 1.133 | 2.586 | 0.0107 |
 ≥ 5 years (181) | 1.578 | 1.053 | 2.365 | 0.0271 | 1.587 | 1.051 | 2.398 | 0.0282 |
Simvastatin (2711) | 1.669 | 1.531 | 1.819 | <  0.0001 | 1.794 | 1.567 | 2.055 | < 0.0001 |
 < 2 years (310) | 0.93 | 0.802 | 1.078 | 0.3341 | 0.912 | 0.776 | 1.071 | 0.2617 |
 2–5 years (290) | 0.988 | 0.846 | 1.155 | 0.8804 | 0.979 | 0.824 | 1.163 | 0.8103 |
 ≥ 5 years (2111) | 1.967 | 1.701 | 2.274 | <  0.0001 | 1.916 | 1.647 | 2.228 | < 0.0001 |