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Table 4 Predictors of MACCE and repeat revascularization in all patients, non-diabetic and diabetic patients on univariable analysis

From: Impact of coronary collateralization on long-term clinical outcomes in type 2 diabetic patients after successful recanalization of chronic total occlusion

VariableAll patientsNon-diabetesDiabetes
MACCERepeat revascularizationMACCERepeat revascularizationMACCERepeat revascularization
Hazard ratio (95% CI)p valueHazard ratio (95% CI)p valueHazard ratio (95% CI)p valueHazard ratio (95% CI)p valueHazard ratio (95% CI)p valueHazard ratio (95% CI)p value
Age1.009 (0.994–1.025)0.2330.997 (0.981–1.013)0.6840.998 (0.977–1.020)0.8880.989 (0.967–1.012)0.3551.019 (0.998–1.041)0.0721.004 (0.981–1.028)0.740
Gender0.876 (0.593–1.294)0.5070.858 (0.565–1302)0.4711.421 (0.704–2.868)0.3271.670 (0.759–3.673)0.2020.733 (0.450–1.193)0.2110.640 (0.380–1.077)0.093
Hypertension1.250 (0.854–1831)0.2521.325 (0.874–2.009)0.1851.030 (0.619–1.713)0.9091.005 (0.589–1.717)0.9841.377 (0.755–2.510)0.2971.767 (0.870–3.590)0.115
Diabetes1.823 (1.313–2.530)< 0.0011.709 (1.202–2.429)0.003        
Current smoking0.820 (0.578–1.165)0.2680.852 (0.586–1.238)0.4000.750 (0.445–1.266)0.2820.809 (0.470–1.394)0.4460.884 (0.547–1.429)0.6160.906 (0.537–1.530)0.712
Hypercholesterolemia1.838 (1.227–2.754)0.0031.847 (1.196–2.852)0.0061.973 (1.076–3.619)0.0281.830 (0.951–3.522)0.0711.515 (0.877–2.615)0.1361.642 (0.913–2.955)0.098
Body mass index (kg/m2)1.032 (0.980–1.085)0.2321.035 (0.980–1.094)0.2120.985 (0.914–1.062)0.7011.010 (0.933–1.093)0.8071.071 (1.000–1.147)0.0501.057 (0.980–1.140)0.150
Glomerular filtration rate (ml/min)0.994 (0.986–1.003)0.1860.999 (0.990–1.007)0.7900.999 (0.986–1.012)0.9021.002 (0.988–1.015)0.8170.990 (0.979–1.001)0.0840.996 (0.985–1.007)0.480
LVEF (%),at baseline0.975 (0.954–0.997)0.0260.972 (0.949–0.995)0.0170.991 (0.959–1.025)0.6050.986 (0.952–1.021)0.4190.971 (0.941–1.001)0.0550.967 (0.936–1.000)0.048
Severity of coronary artery disease1.277 (1.017–1.604)0.0351.272 (0.996–1.624)0.0541.414 (1.019–1.961)0.0381.363 (0.967–1.920)0.0770.981 (0.708–1.358)0.9071.010 (0.706–1.445)0.956
Complete revascularization (%)1.840 (1.275–2.655)0.0011.788 (1.203–2.657)0.0042.604 (1.595–4.252)< 0.0012.540 (1.511–4.269)< 0.0011.310 (0.730–2.352)0.3651.216 (0.631–2.341)0.559
Collateral Rentrop class1.448 (1.040–2.016)0.0281.459 (1.022–2.082)0.0372.013 (1.226–3.304)0.0062.156 (1.279–3.634)0.0040.863 (0.541–1.375)0.5340.827 (0.496–1.380)0.468
  1. MACCE: major adverse cardio-cerebral events; LVEF: left ventricular ejection fraction
  2. Percent event-free from MACCE and repeat revascularization in non-diabetic and type 2 diabetic patients (A and B) and in those with good and poor coronary collateral circulation (C and D). MACCE: major adverse cardio-cerebral events