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Table 4 Predictors of MACCE and repeat revascularization in all patients, non-diabetic and diabetic patients on univariable analysis

From: Impact of coronary collateralization on long-term clinical outcomes in type 2 diabetic patients after successful recanalization of chronic total occlusion

Variable

All patients

Non-diabetes

Diabetes

MACCE

Repeat revascularization

MACCE

Repeat revascularization

MACCE

Repeat revascularization

Hazard ratio (95% CI)

p value

Hazard ratio (95% CI)

p value

Hazard ratio (95% CI)

p value

Hazard ratio (95% CI)

p value

Hazard ratio (95% CI)

p value

Hazard ratio (95% CI)

p value

Age

1.009 (0.994–1.025)

0.233

0.997 (0.981–1.013)

0.684

0.998 (0.977–1.020)

0.888

0.989 (0.967–1.012)

0.355

1.019 (0.998–1.041)

0.072

1.004 (0.981–1.028)

0.740

Gender

0.876 (0.593–1.294)

0.507

0.858 (0.565–1302)

0.471

1.421 (0.704–2.868)

0.327

1.670 (0.759–3.673)

0.202

0.733 (0.450–1.193)

0.211

0.640 (0.380–1.077)

0.093

Hypertension

1.250 (0.854–1831)

0.252

1.325 (0.874–2.009)

0.185

1.030 (0.619–1.713)

0.909

1.005 (0.589–1.717)

0.984

1.377 (0.755–2.510)

0.297

1.767 (0.870–3.590)

0.115

Diabetes

1.823 (1.313–2.530)

< 0.001

1.709 (1.202–2.429)

0.003

        

Current smoking

0.820 (0.578–1.165)

0.268

0.852 (0.586–1.238)

0.400

0.750 (0.445–1.266)

0.282

0.809 (0.470–1.394)

0.446

0.884 (0.547–1.429)

0.616

0.906 (0.537–1.530)

0.712

Hypercholesterolemia

1.838 (1.227–2.754)

0.003

1.847 (1.196–2.852)

0.006

1.973 (1.076–3.619)

0.028

1.830 (0.951–3.522)

0.071

1.515 (0.877–2.615)

0.136

1.642 (0.913–2.955)

0.098

Body mass index (kg/m2)

1.032 (0.980–1.085)

0.232

1.035 (0.980–1.094)

0.212

0.985 (0.914–1.062)

0.701

1.010 (0.933–1.093)

0.807

1.071 (1.000–1.147)

0.050

1.057 (0.980–1.140)

0.150

Glomerular filtration rate (ml/min)

0.994 (0.986–1.003)

0.186

0.999 (0.990–1.007)

0.790

0.999 (0.986–1.012)

0.902

1.002 (0.988–1.015)

0.817

0.990 (0.979–1.001)

0.084

0.996 (0.985–1.007)

0.480

LVEF (%),at baseline

0.975 (0.954–0.997)

0.026

0.972 (0.949–0.995)

0.017

0.991 (0.959–1.025)

0.605

0.986 (0.952–1.021)

0.419

0.971 (0.941–1.001)

0.055

0.967 (0.936–1.000)

0.048

Severity of coronary artery disease

1.277 (1.017–1.604)

0.035

1.272 (0.996–1.624)

0.054

1.414 (1.019–1.961)

0.038

1.363 (0.967–1.920)

0.077

0.981 (0.708–1.358)

0.907

1.010 (0.706–1.445)

0.956

Complete revascularization (%)

1.840 (1.275–2.655)

0.001

1.788 (1.203–2.657)

0.004

2.604 (1.595–4.252)

< 0.001

2.540 (1.511–4.269)

< 0.001

1.310 (0.730–2.352)

0.365

1.216 (0.631–2.341)

0.559

Collateral Rentrop class

1.448 (1.040–2.016)

0.028

1.459 (1.022–2.082)

0.037

2.013 (1.226–3.304)

0.006

2.156 (1.279–3.634)

0.004

0.863 (0.541–1.375)

0.534

0.827 (0.496–1.380)

0.468

  1. MACCE: major adverse cardio-cerebral events; LVEF: left ventricular ejection fraction
  2. Percent event-free from MACCE and repeat revascularization in non-diabetic and type 2 diabetic patients (A and B) and in those with good and poor coronary collateral circulation (C and D). MACCE: major adverse cardio-cerebral events