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Table 1 Baseline characteristics of SBI (+) and SBI (−) groups

From: High triglyceride-glucose index is associated with subclinical cerebral small vessel disease in a healthy population: a cross-sectional study

 

No SBI (n = 2406)

SBI (n = 209)

P-value

Age, years [IQR]

56 [50–62]

63 [57–68]

< 0.001

Sex, male, n (%)

1273 (53)

113 (54)

0.748

Body mass index, kg/m2 [IQR]

23.89 [22.09–25.77]

23.97 [21.99–26.09]

0.504

Use of antihypertensives, n (%)

415 (17)

59 (28)

< 0.001

Use of antiplatelet agents, n (%)

185 (8)

25 (12)

0.029

Systolic BP, mmHg [IQR]

125 [115–135]

131 [120–142]

< 0.001

Diastolic BP, mmHg [IQR]

75 [69–83]

78 [70–87]

< 0.001

Hemoglobin A1c,  % [IQR]

5.7 [5.5–5.9]

5.8 [5.5–6.2]

< 0.001

Fasting glucose, mg/dL [IQR]

91 [84–99]

92 [85–105]

0.015

Insulin, µU/mL [IQR]*

6.5 [4.1–8.9]

6.9 [4.6–9.7]

0.057

HOMA-IR [IQR]*

1.46 [0.89–2.09]

1.58 [1.01–2.34]

0.022

Total cholesterol, mg/dL [SD]

203 ± 36

197 ± 35

0.030

LDL cholesterol, mg/dL [IQR]

129 [107–151]

121 [97–150]

0.041

HDL cholesterol, mg/dL [IQR]

54 [45–64]

51 [44–61]

0.043

Triglyceride, mg/dL [IQR]

98 [72–140]

104 [77–145]

0.041

WBC counts, × 103/μL [IQR]

5.25 [4.34–6.30]

5.47 [4.51–6.55]

0.051

hs-CRP, mg/dL [IQR]

0.04 [0.01–0.14]

0.08 [0.01–0.18]

0.024

TyG index [IQR]

  

0.007

  1. SBI: silent brain infarct; BP: blood pressure; HOMA-IR: Homeostatic Model Assessment for Insulin Resistance; LDL: low-density lipoprotein; HDL: high-density lipoprotein; WBC: white blood cell; hs-CRP: high-sensitivity C-reactive protein; TyG index: triglyceride-glucose index
  2. *These variables were measured in 2051 participants