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Table 1 Baseline characteristics of SBI (+) and SBI (−) groups

From: High triglyceride-glucose index is associated with subclinical cerebral small vessel disease in a healthy population: a cross-sectional study

 No SBI (n = 2406)SBI (n = 209)P-value
Age, years [IQR]56 [50–62]63 [57–68]< 0.001
Sex, male, n (%)1273 (53)113 (54)0.748
Body mass index, kg/m2 [IQR]23.89 [22.09–25.77]23.97 [21.99–26.09]0.504
Use of antihypertensives, n (%)415 (17)59 (28)< 0.001
Use of antiplatelet agents, n (%)185 (8)25 (12)0.029
Systolic BP, mmHg [IQR]125 [115–135]131 [120–142]< 0.001
Diastolic BP, mmHg [IQR]75 [69–83]78 [70–87]< 0.001
Hemoglobin A1c,  % [IQR]5.7 [5.5–5.9]5.8 [5.5–6.2]< 0.001
Fasting glucose, mg/dL [IQR]91 [84–99]92 [85–105]0.015
Insulin, µU/mL [IQR]*6.5 [4.1–8.9]6.9 [4.6–9.7]0.057
HOMA-IR [IQR]*1.46 [0.89–2.09]1.58 [1.01–2.34]0.022
Total cholesterol, mg/dL [SD]203 ± 36197 ± 350.030
LDL cholesterol, mg/dL [IQR]129 [107–151]121 [97–150]0.041
HDL cholesterol, mg/dL [IQR]54 [45–64]51 [44–61]0.043
Triglyceride, mg/dL [IQR]98 [72–140]104 [77–145]0.041
WBC counts, × 103/μL [IQR]5.25 [4.34–6.30]5.47 [4.51–6.55]0.051
hs-CRP, mg/dL [IQR]0.04 [0.01–0.14]0.08 [0.01–0.18]0.024
TyG index [IQR]  0.007
  1. SBI: silent brain infarct; BP: blood pressure; HOMA-IR: Homeostatic Model Assessment for Insulin Resistance; LDL: low-density lipoprotein; HDL: high-density lipoprotein; WBC: white blood cell; hs-CRP: high-sensitivity C-reactive protein; TyG index: triglyceride-glucose index
  2. *These variables were measured in 2051 participants