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Table 2 Changes of CrCl during intravenous infusion of GLP-1

From: GLP-1 mediated diuresis and natriuresis are blunted in heart failure and restored by selective afferent renal denervation

 Sham
(n = 5)
HF
(n = 5)
Sham + T-RDN (n = 5)HF + T-RDN (n = 5)
CrCl (µl/min/gkw)
 Baseline1356 ± 109817 ± 1011893 ± 1371858 ± 215
 20 min2225 ± 94*1725 ± 108*2978 ± 213*2868 ± 178*
  1. Values are mean ± SEM; n = 5 for each group of rats
  2. CrCl creatinine clearance
  3. *P < 0.05 compared to baseline. P < 0.05 compared between Sham and HF. P < 0.05 compared between the group with and without T-RDN