Skip to main content

Table 2 Changes of CrCl during intravenous infusion of GLP-1

From: GLP-1 mediated diuresis and natriuresis are blunted in heart failure and restored by selective afferent renal denervation

  Sham
(n = 5)
HF
(n = 5)
Sham + T-RDN (n = 5) HF + T-RDN (n = 5)
CrCl (µl/min/gkw)
 Baseline 1356 ± 109 817 ± 101 1893 ± 137 1858 ± 215
 20 min 2225 ± 94* 1725 ± 108* 2978 ± 213* 2868 ± 178*
  1. Values are mean ± SEM; n = 5 for each group of rats
  2. CrCl creatinine clearance
  3. *P < 0.05 compared to baseline. P < 0.05 compared between Sham and HF. P < 0.05 compared between the group with and without T-RDN