Table 4 Hazard ratios and 95% confidence intervals of cardiovascular events (myocardial infarction or stroke) by 10 categories of fasting glucose level at baseline stratified by Charlson co-morbidity index (CCI)
Cardiovascular events | ||||||||
|---|---|---|---|---|---|---|---|---|
Fasting glucose (mg/dL) | Number of subjects | Number of event | Follow-up duration (person-years) | Incident rate (per 1000 person-years) | Crude hazard ratio (95% confidence interval) | Adjusted hazard ratioa (95% confidence interval) | P for interaction | |
CCI (≤ 2) | ≤ 79 | 579 | 36 | 3231.06 | 11.14 | 1.17 (0.84–1.63) | 1.09 (0.78–1.51) | 0.04 |
80–94 | 4344 | 250 | 24,425.72 | 10.24 | 1.07 (0.93–1.23) | 1.04 (0.91–1.19) | ||
95–109 | 13,120 | 715 | 74,074.88 | 9.65 | 1.01 (0.92–1.11) | 1.00 (0.91–1.10) | ||
110–124 | 19,268 | 1050 | 109,502.23 | 9.59 | 1 (reference) | 1 (reference) | ||
125–139 | 21,556 | 1230 | 121,947.97 | 10.09 | 1.05 (0.97–1.14) | 1.05 (0.97–1.14) | ||
140–154 | 13,930 | 895 | 78,409.27 | 11.41 | 1.19 (1.09–1.30) | 1.16 (1.06–1.27) | ||
155–169 | 7284 | 529 | 40,701.97 | 13.00 | 1.36 (1.22–1.51) | 1.29 (1.16–1.44) | ||
170–184 | 4046 | 338 | 22,453.28 | 15.05 | 1.57 (1.39–1.78) | 1.51 (1.34–1.71) | ||
185–199 | 2349 | 204 | 12,856.68 | 15.87 | 1.66 (1.43–1.93) | 1.54 (1.33–1.79) | ||
≥ 200 | 3484 | 366 | 18,811.37 | 19.46 | 2.04 (1.81–2.29) | 1.90 (1.69–2.14) | ||
CCI (≥ 3) | ≤ 79 | 1334 | 142 | 6965.54 | 20.39 | 1.44 (1.22–1.71) | 1.32 (1.11–1.56) | |
80–94 | 8807 | 813 | 47,139.49 | 17.25 | 1.22 (1.13–1.33) | 1.16 (1.07–1.26) | ||
95–109 | 23,801 | 1830 | 130,391.96 | 14.03 | 1.00 (0.94–1.06) | 0.99 (0.93–1.05) | ||
110–124 | 31,760 | 2453 | 174,716.38 | 14.04 | 1 (reference) | 1 (reference) | ||
125–139 | 28,913 | 2310 | 158,559.08 | 14.57 | 1.04 (0.98–1.10) | 1.05 (0.99–1.11) | ||
140–154 | 17,833 | 1497 | 97,088.2 | 15.42 | 1.10 (1.03–1.17) | 1.09 (1.02–1.16) | ||
155–169 | 10,097 | 963 | 54,524.43 | 17.66 | 1.26 (1.17–1.35) | 1.21 (1.13–1.31) | ||
170–184 | 6021 | 611 | 32,207.01 | 18.97 | 1.35 (1.24–1.48) | 1.29 (1.18–1.41) | ||
185–199 | 3659 | 409 | 19,277.25 | 21.22 | 1.51 (1.36–1.67) | 1.42 (1.28–1.58) | ||
≥ 200 | 5753 | 765 | 29,498.8 | 25.93 | 1.83 (1.69–1.99) | 1.68 (1.55–1.82) | ||