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Table 6 Change in cardiovascular and diabetic drug therapy 1 year post scan based on having a normal or abnormal stress perfusion cardiac magnetic resonance (CMR) examination

From: Cardiac magnetic resonance for asymptomatic patients with type 2 diabetes and cardiovascular high risk (CATCH): a pilot study

 

1 year change in medications

 

Normal CMR (n = 36)

Abnormal CMR (n = 27)

p

Anti-hypertensives

 Beta-blockers

+2

+4

0.39

 ACE inhibitor

+1

+3

0.80

 Calcium channel blockers

−1

+4

0.03*

 Alpha-blockers

0

+2

0.76

 Diuretics

0

+3

0.07

 ARB

+1

0

1.00

Lipid-modifying agents

 Statin

+1

+8

0.01*

 Fibrates

0

0

1.00

Anti-hyperglycaemic agents

 Acarbose

−1

+1

0.68

 Sulfonylureas

0

0

1.00

 SGLT-2 inhibitor

+2

+3

0.64

 Metformin

+1

+1

1.00

 DDP-4 inhibitor

+2

−1

0.23

 Insulin

0

+1

0.68

 Pioglitazone

+3

+2

1.00

Anti-platelet agents

 Clopidogrel

0

+8

0.001*

 Aspirin

0

+12

< 0.001*

  1. Abnormal stress CMR was defined as having a stress perfusion defect and/or infarct
  2. ACE angiotension converting enzyme, ARB angiotensin receptor blocker, SGLT-2 sodium-glucose co-transport 2 inhibitor, DDP-4 dipeptidyl peptidase-4
  3. *p < 0.05