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Table 4 The hazard ratios (95% CIs) and significance levels of retinopathy presence and severity for an adjusted Cox model and when added to the most parsimonious Cox model for myocardial infarction with age as the timeline

From: Retinopathy predicts stroke but not myocardial infarction in type 2 diabetes: the Fremantle Diabetes Study Phase II

 

Unadjusted model, HR (95% CI)

p-value

Most parsimonious model, HR (95% CI)a

p-value

Any retinopathy

2.10 (1.48, 2.99)

< 0.001

1.30 (0.87, 1.92)

0.197

Retinopathy severity

 None or mild NPDR

1.00 (reference)

 

1.00 (reference)

 

 Moderate NPDR

3.15 (1.74, 5.69)

< 0.001

1.73 (0.91, 3.29)

0.095

 Severe NPDR or worse

3.11 (1.56, 6.22)

0.001

1.02 (0.48, 2.18)

0.958

Moderate NPDR or worse vs mild NPDR or no DR

2.88 (1.80, 4.58)

< 0.001

1.32 (0.78, 2.25)

0.302

  1. aAdjusted for most parsimonious model which comprised age at diabetes diagnosis, HbA1c, current smoker, ln(NT-proBNP), angina and peripheral arterial disease