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Fig. 6 | Cardiovascular Diabetology

Fig. 6

From: Sodium-glucose cotransporter 2 inhibitors antagonize lipotoxicity in human myeloid angiogenic cells and ADP-dependent activation in human platelets: potential relevance to prevention of cardiovascular events

Fig. 6

Effects of NHE inhibition on platelet activation. Surface expressions of αIIbβ3 complex, recognized by PAC1 binding (a), and CD62p (b) were assessed on resting platelets (R) and platelets activated with 5 µM ADP, alone (ADP) or in combination with Amiloride 100 µM (ADP + AMIL) or with Cariporide 10 µM (ADP + CARI), by flow cytometry. Data are expressed as mean of positive platelets (%) ± SEM from at least 3 independent experiments. #p < 0.05 vs R; *p < 0.05 vs ADP; §p < 0.05 vs ADP + AMIL

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Cardiovascular Diabetology

ISSN: 1475-2840