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Table 4 Fibrinogen levels in relation to cardiovascular events in patients with different glucose metabolism status

From: Fibrinogen is associated with glucose metabolism and cardiovascular outcomes in patients with coronary artery disease

 Events/subjectsHR (95% CI)
476/5237Crude modelAdjusted model
NGR
 Low Fib25/510ReferenceReference
 Medium Fib28/3651.56 (0.91–2.67)1.47 (0.85–2.52)
 High Fib23/2701.81 (1.03–3.18)*1.56 (0.87–2.80)
Pre-DM
 Low Fib55/7911.36 (0.85–2.19)1.24 (0.78–2.00)
 Medium Fib72/8141.81 (1.15–2.85)*1.58 (0.99–2.51)
 High Fib81/8501.95 (1.25–3.05)*1.61 (1.01–2.59) *
DM
 Low Fib45/4452.09 (1.28–3.41)*1.81 (1.13–2.92) *
 Medium Fib60/5672.15 (1.35–3.43)*1.86 (1.14–3.05) *
 High Fib87/6252.89 (1.85–4.50)*2.28 (1.42–3.66) *
  1. Model adjusted for age, sex, body mass index, smoking, hypertension, family history of coronary artery disease, left ventricular ejection fraction, low density lipoprotein cholesterol, high lipoprotein cholesterol, Ln-transformed triglyceride, Ln-transformed high-sensitivity C-reactive protein, and creatinine. * p-value < 0.05. Fib fibrinogen, NGR normal glucose regulation, Pre-DM pre-diabetes mellitus, DM diabetes mellitus