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Table 4 Fibrinogen levels in relation to cardiovascular events in patients with different glucose metabolism status

From: Fibrinogen is associated with glucose metabolism and cardiovascular outcomes in patients with coronary artery disease

  Events/subjects HR (95% CI)
476/5237 Crude model Adjusted model
NGR
 Low Fib 25/510 Reference Reference
 Medium Fib 28/365 1.56 (0.91–2.67) 1.47 (0.85–2.52)
 High Fib 23/270 1.81 (1.03–3.18)* 1.56 (0.87–2.80)
Pre-DM
 Low Fib 55/791 1.36 (0.85–2.19) 1.24 (0.78–2.00)
 Medium Fib 72/814 1.81 (1.15–2.85)* 1.58 (0.99–2.51)
 High Fib 81/850 1.95 (1.25–3.05)* 1.61 (1.01–2.59) *
DM
 Low Fib 45/445 2.09 (1.28–3.41)* 1.81 (1.13–2.92) *
 Medium Fib 60/567 2.15 (1.35–3.43)* 1.86 (1.14–3.05) *
 High Fib 87/625 2.89 (1.85–4.50)* 2.28 (1.42–3.66) *
  1. Model adjusted for age, sex, body mass index, smoking, hypertension, family history of coronary artery disease, left ventricular ejection fraction, low density lipoprotein cholesterol, high lipoprotein cholesterol, Ln-transformed triglyceride, Ln-transformed high-sensitivity C-reactive protein, and creatinine. * p-value < 0.05. Fib fibrinogen, NGR normal glucose regulation, Pre-DM pre-diabetes mellitus, DM diabetes mellitus