Skip to main content

Table 3 Relation of the fibrinogen level and cardiovascular outcomes in univariate and multivariate survival analysis

From: Fibrinogen is associated with glucose metabolism and cardiovascular outcomes in patients with coronary artery disease

Variables

Univariate Cox regression

Multivariate Cox regression

Hazard ratio (95% CI)

P value

Hazard ratio (95% CI)

P value

MACE

 Fib (per SD change)

1.18 (1.09–1.27)

< 0.001

1.11 (1.01–1.24)

0.034

 Low Fib

Reference

–

Reference

–

 Medium Fib

1.30 (1.03–1.64)

0.029

1.15 (0.90–1.47)

0.274

 High Fib

1.57 (1.26–1.97)

< 0.001

1.34 (1.02–1.75)

0.035

Composite endpoints

 Fib (per SD change)

1.26 (1.13–1.40)

< 0.001

1.17 (1.02–1.34)

0.023

 Low Fib

Reference

–

Reference

–

 Medium Fib

1.49 (1.06–2.10)

0.022

1.24 (0.87–1.77)

0.243

 High Fib

2.05 (1.49–2.84)

< 0.001

1.67 (1.14–2.45)

0.008

  1. Fib fibrinogen. Model adjusted for age, sex, body mass index, smoking, hypertension, family history of coronary artery disease, left ventricular ejection fraction, low density lipoprotein cholesterol, high lipoprotein cholesterol, Ln-transformed triglyceride, Ln-transformed high-sensitivity C-reactive protein, and creatinine
Back to article page

Cardiovascular Diabetology

ISSN: 1475-2840