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Table 3 Relation of the fibrinogen level and cardiovascular outcomes in univariate and multivariate survival analysis

From: Fibrinogen is associated with glucose metabolism and cardiovascular outcomes in patients with coronary artery disease

Variables Univariate Cox regression Multivariate Cox regression
Hazard ratio (95% CI) P value Hazard ratio (95% CI) P value
MACE
 Fib (per SD change) 1.18 (1.09–1.27) < 0.001 1.11 (1.01–1.24) 0.034
 Low Fib Reference Reference
 Medium Fib 1.30 (1.03–1.64) 0.029 1.15 (0.90–1.47) 0.274
 High Fib 1.57 (1.26–1.97) < 0.001 1.34 (1.02–1.75) 0.035
Composite endpoints
 Fib (per SD change) 1.26 (1.13–1.40) < 0.001 1.17 (1.02–1.34) 0.023
 Low Fib Reference Reference
 Medium Fib 1.49 (1.06–2.10) 0.022 1.24 (0.87–1.77) 0.243
 High Fib 2.05 (1.49–2.84) < 0.001 1.67 (1.14–2.45) 0.008
  1. Fib fibrinogen. Model adjusted for age, sex, body mass index, smoking, hypertension, family history of coronary artery disease, left ventricular ejection fraction, low density lipoprotein cholesterol, high lipoprotein cholesterol, Ln-transformed triglyceride, Ln-transformed high-sensitivity C-reactive protein, and creatinine