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Table 5 Relationship between the incidence of the primary endpoint and the TyG index expressed as a categorical variable

From: Triglyceride glucose index for predicting cardiovascular outcomes after percutaneous coronary intervention in patients with type 2 diabetes mellitus and acute coronary syndrome

Variables

Univariate analysis

HR (95% CI)

P value

Multivariate analysis

HR (95% CI)

P-value

TyG index tertiles

 T1

Reference

 

Reference

 

 T2

1.74 (1.17–2.57)

0.006

1.60 (1.06–2.40)

0.025

 T3

2.27 (1.56–3.32)

< 0.001

2.15 (1.44–3.22)

< 0.001

 Age

1.01 (0.99–1.02)

0.458

0.99 (0.97–1.004)

0.138

 BMI

0.98 (0.94–1.02)

0.300

0.97 (0.92–1.01)

0.166

 DBP

0.98 (0.96–0.99)

0.001

0.99 (0.97–1.00)

0.048

 HDL-C

0.98 (0.96–1.00)

0.014

0.98 (0.96–1.00)

0.042

 Glycosylated haemoglobin

1.05 (0.94–1.18)

0.387

0.93 (0.82–1.06)

0.307

 Male sex

0.92 (0.67–1.26)

0.603

0.68 (0.44–1.04)

0.077

 Current smoking

0.94 (0.70–1.27)

0.699

1.02 (0.71–1.46)

0.918

 Daily drinking

1.01 (0.62–1.65)

0.957

1.30 (0.77–2.18)

0.330

 Previous MI

1.52 (1.11–2.09)

0.009

0.88 (0.61–1.27)

0.500

 Past PCI

1.79 (1.33–2.41)

< 0.001

1.72 (1.17–2.53)

0.006

 PAD

2.82 (2.05–3.87)

< 0.001

2.22 (1.52–3.24)

< 0.001

 CKD

1.70 (1.07–2.70)

0.025

1.46 (0.85–2.52)

0.172

 Cardiac failure

2.27 (1.52–3.40)

< 0.001

1.59 (1.00–2.52)

0.049

 Insulin at discharge

1.39 (1.04–1.87)

0.025

0.95 (0.67–1.36)

0.797

 Metformin at discharge

1.12 (0.76–1.63)

0.568

1.08 (0.72–1.62)

0.707

 Alpha-glucosidase inhibitors at discharge

0.89 (0.66–1.21)

0.457

0.76 (0.55–1.06)

0.104

 Sulfonylurea at discharge

0.89 (0.64–1.26)

0.524

0.95 (0.65–1.38)

0.784

 Dipeptidyl peptidase 4 inhibitors at discharge

1.34 (0.50–3.60)

0.566

1.24 (0.44–3.48)

0.685

CAD severity

 One-vessel disease

Reference

 

Reference

 

 Two-vessel disease

2.08 (0.87–5.01)

0.101

1.30 (0.52–3.24)

0.579

 LM/three-vessel disease

4.32 (1.91–9.76)

< 0.001

2.16 (0.91–5.13)

0.079

 Lesions > 20 mm long

2.07 (1.51–2.84)

< 0.001

1.59 (1.13–2.23)

0.008

 DCB use

2.07 (1.33–3.23)

0.001

1.23 (0.73–2.08)

0.430

 Complete revascularization

0.46 (0.35–0.62)

< 0.001

0.63 (0.46–0.86)

0.004

  1. Abbreviations as in Tables 1 and 2