Table 1 Baseline clinical and laboratory characteristics of the study patients stratified by the primary endpoint
Variable | No such events n = 588 | Primary endpoint n = 188 | P value |
|---|---|---|---|
Demographics | |||
 Age (years) | 61 ± 10 | 62 ± 10 | 0.498 |
 Male sex, n (%) | 426 (72.4) | 134 (71.3) | 0.755 |
 BMI (kg/m2) | 26.2 ± 3.5 | 25.9 ± 3.1 | 0.298 |
Medical measurements (on admission) | Â | Â | Â |
 SBP (mm Hg) | 132 ± 18 | 131 ± 15 | 0.339 |
 DBP (mm Hg) | 76 ± 11 | 73 ± 10 | 0.001 |
Risk factors | |||
 Cigarette smoking |  |  |  |
  Current smokers, n (%) | 238 (40.5) | 72 (38.3) | 0.596 |
  Former smokers, n (%) | 89 (15.1) | 35 (18.6) | 0.257 |
  Never smokers, n (%) | 261 (44.4) | 81 (43.1) | 0.754 |
 Alcohol intake | |||
  Daily drinkers, n (%) | 56 (9.5) | 18 (9.6) | 0.984 |
 Family history of CHD, n (%) | 172 (29.3) | 66 (35.1) | 0.130 |
 Hypertension, n (%) | 403 (68.5) | 129 (68.6) | 0.984 |
 Dyslipidaemia, n (%) | 483 (82.1) | 163 (86.7) | 0.145 |
 Previous MI, n (%) | 112 (19.0) | 54 (28.7) | 0.005 |
 Past PCI, n (%) | 120 (20.4) | 66 (35.1) | < 0.001 |
 Previous CVA, n (%) | 37 (6.3) | 11 (5.9) | 0.827 |
 PAD, n (%) | 62 (10.5) | 54 (28.7) | < 0.001 |
 CKD, n (%) | 40 (6.8) | 20 (10.6) | 0.087 |
 Cardiac failure, n (%) | 34 (5.8) | 28 (14.9) | < 0.001 |
 LVEF (%) | 65 (60-68) | 63 (58-68) | 0.016 |
Clinical presentation | |||
 UA, n (%) | 457 (77.7) | 153 (81.4) | 0.287 |
 NSTEMI, n (%) | 82 (13.9) | 18 (9.6) | 0.119 |
 STEMI, n (%) | 49 (8.3) | 17 (9.0) | 0.762 |
Laboratory measurements (fasting state) | |||
 TC (mg/dL) | 157.6 ± 42.5 | 156.0 ± 37.4 | 0.638 |
 LDL-C (mg/dL) | 93.8 ± 34.9 | 91.6 ± 29.5 | 0.445 |
 HDL-C (mg/dL) | 39.8 ± 9.1 | 37.9 ± 7.9 | 0.008 |
 Triglycerides (mg/dL) | 128.4 (92.1–176.2) | 145.2 (97.4–201.9) | 0.039 |
 FPG (mg/dL) | 123.8 (109.9–147.2) | 138.5 (114.2–169.4) | < 0.001 |
 Glycosylated haemoglobin (%) | 7.2 (6.6–8.1) | 7.3 (6.8–8.2) | 0.140 |
 TyG index | 9.02 ± 0.57 | 9.21 ± 0.53 | < 0.001 |
 TyG index tertiles |  |  | < 0.001 |
  T1, n (%) | 217 (36.9) | 40 (21.3) | – |
  T2, n (%) | 194 (33.0) | 66 (35.1) | – |
  T3, n (%) | 177 (30.1) | 82 (43.6) | – |