Table 2 Risks of hospitalized IS/SE and major bleeding among AF patients in different HbA1c categories
From: Glycemic status and risks of thromboembolism and major bleeding in patients with atrial fibrillation
| Â | Event rate/100 person-years (95% CI) | Crude | Adjusted | ||
|---|---|---|---|---|---|
HR (95% CI) | P value | HR (95% CI)a | P value | ||
IS/SE | |||||
 HbA1c < 5.4 | 1.20 (1.04–1.36) | 1.00 (Reference) | – | 1.00 (Reference) | – |
 HbA1c 5.4–5.6 | 1.33 (1.20–1.47) | 1.06 (0.9–1.26) | 0.4926 | 1.08 (0.92–1.28) | 0.3508 |
 HbA1c 5.7–5.9 | 1.41 (1.29–1.54) | 1.1 (0.93–1.29) | 0.2576 | 1.12 (0.96–1.32) | 0.1571 |
 HbA1c 6.0–6.4 | 1.31 (1.20–1.42) | 1.02 (0.87–1.2) | 0.7701 | 1.04 (0.88–1.22) | 0.6659 |
 HbA1c 6.5–6.9 | 1.47 (1.31–1.63) | 1.21 (1.01–1.43) | 0.0341 | 1.2 (1–1.43) | 0.0450 |
 HbA1c 7.0–7.9 | 1.55 (1.40–1.71) | 1.32 (1.12–1.56) | 0.0011 | 1.32 (1.11–1.57) | 0.0019 |
 HbA1c ≥ 8.0 | 1.53 (1.39–1.67) | 1.39 (1.18–1.63) | < 0.0001 | 1.48 (1.25–1.76) | < 0.0001 |
| Â | Event rate/100 person-years (95% CI) | Crude | Adjusted | HR (95% CI)b | P value |
|---|---|---|---|---|---|
HR (95% CI) | P value | ||||
Major bleeding | |||||
 HbA1c < 5.4 | 0.84 (0.71–0.97) | 1.00 (Reference) | – | 1.00 (Reference) | – |
 HbA1c 5.4–5.6 | 0.76 (0.65–0.86) | 0.86 (0.7–1.06) | 0.1554 | 0.9 (0.73–1.11) | 0.3136 |
 HbA1c 5.7–5.9 | 0.75 (0.66–0.84) | 0.84 (0.69–1.02) | 0.0770 | 0.88 (0.72–1.08) | 0.2178 |
 HbA1c 6.0–6.4 | 0.78 (0.69–0.87) | 0.88 (0.72–1.06) | 0.1770 | 0.89 (0.73–1.08) | 0.2353 |
 HbA1c 6.5–6.9 | 0.85 (0.73–0.97) | 1 (0.81–1.24) | 0.9942 | 0.94 (0.76–1.17) | 0.5790 |
 HbA1c 7.0–7.9 | 0.83 (0.72–0.95) | 1.02 (0.83–1.26) | 0.8314 | 0.93 (0.75–1.16) | 0.5121 |
 HbA1c ≥ 8.0 | 0.78 (0.68–0.87) | 1.01 (0.83–1.24) | 0.9151 | 0.92 (0.74–1.15) | 0.4700 |